Name: DG 381B
Brand: TargetMol
SKU: TN8310
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

2 mg

¥ 1,526

待询

生物活性

产品描述	DG 381B (11-Deoxyglycyrrhetinic acid) has anti-inflammatory and potential anticancer activities, significantly inhibiting gastric cancer cell viability in a dose- and time-dependent manner. It induces apoptosis and G2 cell cycle arrest by upregulating p21 and downregulating cdc2 and cyclin B1 in gastric cancer cells.
体外活性	DG 381B 通过上调 p21 和下调 cdc2 和细胞周期蛋白 B1 诱导胃癌细胞凋亡和 G2 期细胞周期停滞，以剂量和时间依赖性方式显著抑制胃癌细胞的活力。[1]
体内活性	DG 381B 可有效抑制裸鼠胃癌细胞的肿瘤形成。[1]
别名	STX122, STX 122, DG381B, 11-Deoxyglycyrrhetinic acid

化学信息

分子量	456.7
分子式	C₃₀H₄₈O₃
CAS No.	564-16-9
Smiles	C[C@]12[C@@]([C@]3(C)[C@@](CC1)(C(C)(C)[C@@H](O)CC3)[H])(CC=C4[C@@]2(C)CC[C@]5(C)[C@]4(C[C@](C(O)=O)(C)CC5)[H])[H]
密度	no data available
颜色	White
物理性状	Solid