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Anti-CDH18 Polyclonal Antibody

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货号 TMAB-04155

Anti-CDH18 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CDH18。Anti-CDH18 Polyclonal Antibody 可用于 FCM。

Anti-CDH18 Polyclonal Antibody

Anti-CDH18 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-04155

Anti-CDH18 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CDH18。Anti-CDH18 Polyclonal Antibody 可用于 FCM。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-CDH18 Polyclonal Antibody is a Rabbit antibody targeting CDH18. Anti-CDH18 Polyclonal Antibody can be used in FCM.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用FCM
推荐剂量
FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding events that are critical to the maintenance of cell structure and morphogenesis. EY-cadherin, also known as CDH18 (cadherin 18), CDH14 (cadherin 14), CDH24 or CDH14L, is a 790 amino acid single-pass type I membrane protein that contains five cadherin domains. One of several members of the cadherin superfamily, EY-cadherin functions as a type II classical cadherin that is expressed specifically in the central nervous system (CNS), where it plays a role in cell-cell binding events. Specifically, EY-cadherin is thought to be involved in axon guidance and outgrowth, as well as synaptic adhesion within the CNS. EY-cadherin contains a highly conserved C-terminal domain characteristic of all cadherins, but lacks the HAV cell adhesion sequence that is specific to type I cadherins. The gene encoding EY-cadherin is located within a region on chromosome five that is commonly deleted in carcinomas, implicating EY-cadherin as a potential tumor suppressor.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CDH18
抗原种属
Human
基因名称
CDH18
基因ID
蛋白名称
Cadherin-18
Uniprot ID
功能
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
化学信息
分子量Theoretical: 82 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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