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Anti-IL-12A Antibody (1X261)
还可以产品编号 TMAY-00087
Anti-IL-12A Antibody (1X261) 是一种 Rabbit 抗体，靶向 IL-12A。Anti-IL-12A Antibody (1X261) 可用于 ELISA。
Anti-IL-12A Antibody (1X261)
Anti-IL-12A Antibody (1X261)
还可以产品编号 TMAY-00087
Anti-IL-12A Antibody (1X261) 是一种 Rabbit 抗体，靶向 IL-12A。Anti-IL-12A Antibody (1X261) 可用于 ELISA。
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偶联与修饰
抗原信息
| 产品描述 | Anti-IL-12A Antibody (1X261) is a Rabbit antibody targeting IL-12A. Anti-IL-12A Antibody (1X261) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 1X261 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human IL12A / IL-12A (rh IL12A / IL-12A; TMPY-01409; P29459; Met 1-Ser 219). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Interleukin-12 subunit alpha (IL12A/IL-12p35) is also known as Cytotoxic lymphocyte maturation factor 35 kDa subunit, cytotoxic lymphocyte maturation factor 1, p35, NK cell stimulatory factor chain 1, and interleukin-12 alpha chain. IL12A/IL-12p35 is a subunit of a cytokine that acts on T and natural killer cells and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. IL12A/IL-12p35 is required for the T-cell-independent induction of interferon (IFN)-gamma and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. In clinical, IL-12 remains a very promising immunotherapeutic agent because recent cancer vaccination studies in animal models and humans have demonstrated its powerful adjuvant properties. The immune-modulating characteristics of IL-12 considered responsible for the adjuvant effects, as well as the results of animal and human cancer vaccination studies with IL-12, applied as an adjuvant. IL12A/IL-12p35 indicates a cytokine that is important in the development of prostate cancer. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human IL12A / IL-12A protein (TMPY-01409) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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