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顶部生物活性储存和溶解信息计算器

Anti-VE-Cadherin Antibody (9S718)

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产品编号 TMAY-00825

别名 cadherin 5, type 2 (vascular endothelium)

Anti-VE-Cadherin Antibody (9S718) 是一种 Rabbit 抗体，靶向 VE-Cadherin。Anti-VE-Cadherin Antibody (9S718) 可用于 IHC-P。

Anti-VE-Cadherin Antibody (9S718)

Anti-VE-Cadherin Antibody (9S718)

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Rating icon 还可以
产品编号 TMAY-00825 别名 cadherin 5, type 2 (vascular endothelium)

Anti-VE-Cadherin Antibody (9S718) 是一种 Rabbit 抗体，靶向 VE-Cadherin。Anti-VE-Cadherin Antibody (9S718) 可用于 IHC-P。

规格价格库存数量
20 μL
¥ 790
5日内发货
100 μL
¥ 2,294
5日内发货
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产品介绍

生物活性
产品描述
Anti-VE-Cadherin Antibody (9S718) is a Rabbit antibody targeting VE-Cadherin. Anti-VE-Cadherin Antibody (9S718) can be used in IHC-P.
别名cadherin 5, type 2 (vascular endothelium)
Ig Type
Rabbit IgG
克隆号
9S718
交叉反应
Human
特异性
Human VE-Cadherin
验证活性
1. Immunochemical staining of human Cad5 in human stomach with rabbit monoclonal antibody (1:500, formalin-fixed paraffin embedded sections).
2. Immunochemical staining of human Cad5 in human kidney with rabbit monoclonal antibody (1:500, formalin-fixed paraffin embedded sections).
应用IHC-P
推荐剂量
IHC-P: 1:250-1:1000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human VE-Cadherin / CD144 (CAA56306.1; Met1-Gln593).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Cadherins (Calcium dependent adhesion molecules) are a class of transmembrane proteins. Cadherin-5, also known as VE-cadherin, CDH5 and CD144, an endothelial specific cell-cell adhesion molecule, plays a pivotal role in the formation, maturation and remodeling of the vascular wall. VE-Cadherin is widely considered to be specific for vascular endothelia in which it is either the sole or the predominant cadherin, often co-existing with N-cadherin. This specificity of VE-cadherin for vascular endothelial cells is important not only in blood and lymph vessel biology and medicine, but also for cell-type-based diagnoses, notably those of metastatic tumors. As a classical cadherin, VE-Cadherin links endothelial cells together by homophilic interactions mediated by its extracellular part and associates intracellularly with the actin cytoskeleton via catenins. Mechanisms that regulate VE-cadherin-mediated adhesion are important for the control of vascular permeability and leukocyte extravasation. In addition to its adhesive functions, VE-Cadherin regulates various cellular processes such as cell proliferation and apoptosis and modulates vascular endothelial growth factor receptor functions. Consequently, VE-cadherin is essential during embryonic angiogenesis.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human VE-Cadherin / CD144 Protein
抗原种属
Human
研究领域
Hemangioblast Markers, Cardiac Stem Cell Markers
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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关键词

vascular endotheliumcadherin 5, type 2

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