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IL-11 Protein, Human, Recombinant (His)
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很棒SPR兼容缓冲液
货号 TMPK-00088
别名 白细胞介素, 白介素, Oprelvekin, Interleukin-11, interleukin 11, INN: Oprelvekin, IL-11Oprelvekin, IL11, AGIF, Adipogenesis inhibitory factor
Abstract Interleukin-11 (IL-11) is a pleiotropic cytokine that belongs to gp130 family. IL-11 and its receptor, IL-11Ra, are expressed in human cancers,human cancer cells expressed a functional IL-11Ra subunit, which triggered signal transduction either by exogenous recombinant human IL-11 or by autocrine production of IL-11 in cells cultured under hypoxic conditions. IL-11 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 20.24 kDa and the accession number is P20809-1.
其他形式的 “IL-11 Protein, Human, Recombinant (His)”:
IL-11 Protein, Human, Recombinant (His)
一键复制产品信息 很棒SPR兼容缓冲液
货号 TMPK-00088 别名 白细胞介素, 白介素, Oprelvekin, Interleukin-11, interleukin 11, INN: Oprelvekin, IL-11Oprelvekin, IL11, AGIF, Adipogenesis inhibitory factor
Abstract Interleukin-11 (IL-11) is a pleiotropic cytokine that belongs to gp130 family. IL-11 and its receptor, IL-11Ra, are expressed in human cancers,human cancer cells expressed a functional IL-11Ra subunit, which triggered signal transduction either by exogenous recombinant human IL-11 or by autocrine production of IL-11 in cells cultured under hypoxic conditions. IL-11 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 20.24 kDa and the accession number is P20809-1.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 223 | 现货 | |
| 10 μg | ¥ 345 | 现货 | |
| 20 μg | ¥ 552 | 现货 | |
| 50 μg | ¥ 1,060 | 3日内发货 | |
| 100 μg | ¥ 1,770 | 现货 | |
| 200 μg | ¥ 3,190 | 5日内发货 | |
| 500 μg | ¥ 7,110 | 5日内发货 |
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纯度: > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
颜色: 白色
性状: Lyophilized powder
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| 产品描述 | Abstract Interleukin-11 (IL-11) is a pleiotropic cytokine that belongs to gp130 family. IL-11 and its receptor, IL-11Ra, are expressed in human cancers,human cancer cells expressed a functional IL-11Ra subunit, which triggered signal transduction either by exogenous recombinant human IL-11 or by autocrine production of IL-11 in cells cultured under hypoxic conditions. IL-11 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 20.24 kDa and the accession number is P20809-1. |
| 生物活性 | 1. Immobilized Human IL-11, His Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Human IL-11 R alpha, hFc Tag with the EC50 of 26.2ng/ml determined by ELISA (QC Test).
2.Human IL-11R alpha, His Tag immobilized on CM5 Chip can bind Human IL-11, His Tag with an affinity constant of 1.86 nM as determined in SPR assay. |
| 研究背景 | Abstract Interleukin-11 (IL-11) is a pleiotropic cytokine that belongs to gp130 family. IL-11 and its receptor, IL-11Ra, are expressed in human cancers,human cancer cells expressed a functional IL-11Ra subunit, which triggered signal transduction either by exogenous recombinant human IL-11 or by autocrine production of IL-11 in cells cultured under hypoxic conditions. |
| 种属 | Human |
| 表达系统 | HEK293 Cells |
| 标签 | N-His |
| 蛋白编号 | P20809-1 |
| 蛋白构建 | Pro22-Leu199 |
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| 蛋白性状 | Lyophilized powder |
| 缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| 复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 别名 | 白细胞介素, 白介素, Oprelvekin, Interleukin-11, interleukin 11, INN: Oprelvekin, IL-11Oprelvekin, IL11, AGIF, Adipogenesis inhibitory factor |
| 内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
| 分子量 | 20.24 kDa (predicted). Due to glycosylation, the protein migrates to 21-25 kDa based on Tris-Bis PAGE result. |
| 运输方式 | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| 存储 |
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