Azoxystrobin

Name: Azoxystrobin
Brand: TargetMol
SKU: T21275
Price: 325 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 99.82%

货号 T21275Cas号 131860-33-8

别名 嘧菌酯, ICIA-5504, ICI-A 5504, HSDB 7017, Bankit, Amistar

Azoxystrobin (Bankit) 是一种广谱杀菌剂。 Azoxystrobin 通过阻断细胞色素 b 和 c1 之间的电子转移来诱导 ROS 产生、细胞凋亡和线粒体呼吸。

Azoxystrobin

一键复制产品信息

很棒

纯度: 99.82%

货号 T21275 别名 嘧菌酯, ICIA-5504, ICI-A 5504, HSDB 7017, Bankit, AmistarCas号 131860-33-8

Azoxystrobin (Bankit) 是一种广谱杀菌剂。 Azoxystrobin 通过阻断细胞色素 b 和 c1 之间的电子转移来诱导 ROS 产生、细胞凋亡和线粒体呼吸。

规格	价格	库存
50 mg	¥ 325	现货
100 mg	¥ 476	现货
500 mg	¥ 1,160	现货
1 mL x 10 mM (in DMSO)	¥ 361	现货

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产品介绍

Azoxystrobin AI Summary

Azoxystrobin exhibits a diverse range of bioactivities, targeting various pathogens and biological pathways. It shows significant antimicrobial activity against several fungi, including high inhibition rates of Fusarium oxysporum, Rhizoctonia solani, and Botrytis cinerea, with notable efficacy at different concentrations and time points. Additionally, it demonstrates potent antifungal effects against Colletotrichum fragariae, characterized by considerable growth inhibition zones, and broad-spectrum fungicidal activities against pathogens like Blumeria graminis and Pseudoperonospora cubensis. Azoxystrobin also inhibits the cytochrome bc1 complex in plant pathogens at low concentrations, suggesting its potential as a broad-spectrum antifungal agent. It exhibits strong antimalarial activity against Plasmodium falciparum, with high inhibition percentages and low IC50 values, indicating its potency against malaria-causing parasites. Furthermore, it shows inhibitory activity against cytochrome complexes in porcine heart tissues, impacting mitochondrial respiration processes. In in vitro assays, Azoxystrobin demonstrates inhibition of Trypanosoma cruzi, indicative of its potential as a treatment for Chagas Disease, with specific IC50 values. Additionally, the compound shows limited cytotoxicity in HepG2 and HEK293 cell lines, making it a candidate for therapeutic applications. The compound also displays notable effects against plant pathogens, inhibiting the growth of strains from Fusarium, Colletotrichum, and Pestalotiopsis species, and demonstrating fungicidal activity in infected plant systems. These multifaceted bioactivities suggest that Azoxystrobin holds promise as a versatile antimicrobial agent with potential applications in agriculture and medicine..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Azoxystrobin (Bankit) is a broad-spectrum fungicide. Azoxystrobin induces ROS production, cell apoptosis and mitochondrial respiration by blocking electron transfer between cytochromes b and c1.
别名	嘧菌酯, ICIA-5504, ICI-A 5504, HSDB 7017, Bankit, Amistar

化学信息

分子量	403.39
分子式	C₂₂H₁₇N₃O₅
CAS No.	131860-33-8
Smiles	C(\C(OC)=O)(=C/OC)/C1=C(OC=2C=C(OC3=C(C#N)C=CC=C3)N=CN2)C=CC=C1
密度	1.34(20°C)

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 262.5 mg/mL (650.74 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (8.18 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4790 mL	12.3950 mL	24.7899 mL	123.9495 mL
5 mM	0.4958 mL	2.4790 mL	4.9580 mL	24.7899 mL
10 mM	0.2479 mL	1.2395 mL	2.4790 mL	12.3950 mL
20 mM	0.1239 mL	0.6197 mL	1.2395 mL	6.1975 mL
50 mM	0.0496 mL	0.2479 mL	0.4958 mL	2.4790 mL
100 mM	0.0248 mL	0.1239 mL	0.2479 mL	1.2395 mL