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Anti-MMP-14 Antibody (7I45)
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产品编号 TMAC-02619
别名 MT-MMP1, MT1MMP), MT1-MMP, MT 1-MMP, MMP-X1, MMPX1, MMP14, Membrane-type matrix metalloproteinase 1 (MT-MMP 1
Anti-MMP-14 Antibody (7I45) 是一种 Rabbit 抗体，靶向 MMP-14。Anti-MMP-14 Antibody (7I45) 可用于 WB,ICC/IF,IHC,IP,FCM。
Anti-MMP-14 Antibody (7I45)
Anti-MMP-14 Antibody (7I45)
还可以产品编号 TMAC-02619 别名 MT-MMP1, MT1MMP), MT1-MMP, MT 1-MMP, MMP-X1, MMPX1, MMP14, Membrane-type matrix metalloproteinase 1 (MT-MMP 1
Anti-MMP-14 Antibody (7I45) 是一种 Rabbit 抗体，靶向 MMP-14。Anti-MMP-14 Antibody (7I45) 可用于 WB,ICC/IF,IHC,IP,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,495 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
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产品介绍
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抗原信息
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| 产品描述 | Anti-MMP-14 Antibody (7I45) is a Rabbit antibody targeting MMP-14. Anti-MMP-14 Antibody (7I45) can be used in WB,ICC/IF,IHC,IP,FCM. |
| 别名 | MT-MMP1, MT1MMP), MT1-MMP, MT 1-MMP, MMP-X1, MMPX1, MMP14, Membrane-type matrix metalloproteinase 1 (MT-MMP 1 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of MMP14 on human kidney tissue lysates using anti-MMP14 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-MMP14 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-MMP14 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human uterus tissue using anti-MMP14 antibody. Counter stained with hematoxylin. 5. ICC staining MMP14 in CRC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 6. ICC staining MMP14 in BT-20 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 7. Flow cytometric analysis of A549 cells with MMP14 antibody at 1/50 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
| 应用 | |
| 推荐剂量 | WB: 1:1000-2000; IHC: 1:100-200; ICC/IF: 1:50-200; IP 1:20-50; FCM 1:20-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. Membrane-type matrix metalloproteinases, including MT-MMP-1 (also designated MMP-14), MT-MMP-2 (also designated MMP-15), MT-MMP-3 (also designated MMP-16) and MT-MMP-4 (also designated MMP-17) are type I membrane proteins that function to activate other MMPs. MT-MMP activation appears to be mediated by members of the proprotein convertase family, suggesting that a proprotein convertase/MT-MMP/MMP cascade may be involved in the regulation of ECM turnover. |
| 偶联 | Unconjugated |
| 免疫原 | A synthesized peptide: human MMP14 |
| 抗原种属 | human |
| Uniprot ID |
| 分子量 | Theoretical: 65 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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