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别名 VGLL 4, VGL 4, Vestigial like protein 4, Transcription cofactor vestigial like protein 4
Anti-VGLL4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 VGLL4。Anti-VGLL4 Polyclonal Antibody 可用于 WB。
Anti-VGLL4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 VGLL4。Anti-VGLL4 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
| 产品描述 | Anti-VGLL4 Polyclonal Antibody is a Rabbit antibody targeting VGLL4. Anti-VGLL4 Polyclonal Antibody can be used in WB. |
| 别名 | VGLL 4, VGL 4, Vestigial like protein 4, Transcription cofactor vestigial like protein 4 |
| Ig Type | IgG |
| 反应种属 | Mouse,Rat (predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep) |
| 验证活性 | 1. Sample: Ovary (Mouse) Lysate at 40 μg Ovary (Rat) Lysate at 40 μg Primary: Anti-VGLL4 (TMAB-01961) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 31 kDa Observed band size: 31 kDa 2. Sample: Lane 1: Mouse Stomach tissue lysates Lane 2: Mouse Lung tissue lysates Lane 3: Mouse Large intestine tissue lysates Primary: Anti-VGLL4 (TMAB-01961) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 31 kDa Observed band size: 31 kDa ![]() ![]() |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nuclear |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 研究背景 | The transcriptional enhancer factor-1 (TEF-1) family of transcription factors regulate tissue-specific gene expression in muscle and placenta. The mechanism whereby TEF-1 confers tissue specificity depends largely on the interaction of TEF-1 with tissue-specific cofactors. Transcription cofactor Vgl-4 (vestigial-like protein 4) is a 290 amino acid nuclear protein that interacts with TEF-1 and MEF-2. Vgl-4 is the only member of the vestigial-like family that is expressed in heart. Overexpression of Vgl-4 in cardiac myocytes interferes with basal expression and ?-adrenergic receptor-dependent activation of a TEF-1 dependent skeletal ?actin promoter. This suggests that Vgl-4 counteracts ?-adrenergic activation of gene expression in cardiomyocytes. There are two isoforms of Vgl-4 that are produced as a result of alternative splicing events. |
| 免疫原 | KLH conjugated synthetic peptide: human VGLL4 |
| 抗原种属 | Human |
| 基因名称 | VGLL4 |
| 基因ID | |
| 蛋白名称 | Transcription cofactor vestigial-like protein 4 |
| Uniprot ID | |
| 研究领域 | Co-factors,Other factors |
| 功能 | May act as a specific coactivator for the mammalian TEFs (By similarity). |
| 分子量 | Theoretical: 31 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | store at -20°C |