Anti-EPCR Antibody (2F25)

Name: Anti-EPCR Antibody (2F25)
Brand: TargetMol
SKU: TMAY-03823
Rating: 4.5 (1 reviews)

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产品编号 TMAY-03823

Anti-EPCR Antibody (2F25) 是一种 Rabbit 抗体，靶向 EPCR。Anti-EPCR Antibody (2F25) 可用于 ELISA。

Anti-EPCR Antibody (2F25)

还可以

产品编号 TMAY-03823

Anti-EPCR Antibody (2F25) 是一种 Rabbit 抗体，靶向 EPCR。Anti-EPCR Antibody (2F25) 可用于 ELISA。

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生物活性

产品描述	Anti-EPCR Antibody (2F25) is a Rabbit antibody targeting EPCR. Anti-EPCR Antibody (2F25) can be used in ELISA.
Ig Type	Monoclonal Rabbit IgG
克隆号	2F25
交叉反应	Rat
应用	ELISA
推荐剂量	ELISA: 1:5000-1:10000
抗体种类	Monoclonal
宿主来源	Rabbit
构建方式	This antibody was obtained from a rabbit immunized with purified, recombinant Rat Epcr / PROCR (rR Epcr / PROCR; TMPY-03347; ; Met1-Ser213).
纯化方式	Protein A
性状	Liquid
缓冲液	0.2 μm filtered solution in PBS
研究背景	Endothelial protein C receptor (EPCR), also known as activated protein C receptor (APC receptor) or PROCR, is a receptor for Protein C. Protein C plays an important role in many metabolism processes in humans and other animals after activated by binding to Endothelial protein C receptor (EPCR). Because of the EPCR is found primarily on endothelial cells (cells on the inside of blood vessels), activated protein C is found mainly near endothelial cells. Protein C is pleiotropic, with two main functions: anticoagulation and cytoprotection. Which function will be performed depending on whether or not protein C remains bind to EPCR after activated. The anticoagulation occurs when it does not. In this case, protein C functions as an anticoagulant by irreversibly proteolytically inactivating Factor Va and Factor VIIIa, turning them into Factor Vi and Factor VIIIi respectively. When still bound to EPCR, activated protein C performs its cytoprotective effects, acting on the effector substrate PAR-1, protease-activated receptor-1. To a degree, APC's anticoagulant properties are independent of its cytoprotective ones, in that expression of one pathway is not affected by the existence of the other.

偶联与修饰

偶联	Unconjugated

抗原信息

免疫原	Recombinant Rat Epcr / PROCR Protein (TMPY-03347)
抗原种属	Rat
研究领域	Serine Proteases and Regulators

存储&运输

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式	Shipping with blue ice.