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Anti-EPCR Antibody (2F25)

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Anti-EPCR Antibody (2F25)
产品编号 TMAY-03823
别名 protein C receptor, endothelial

Anti-EPCR Antibody (2F25) 是一种 Rabbit 抗体,靶向 EPCR。Anti-EPCR Antibody (2F25) 可用于 ELISA。

Anti-EPCR Antibody (2F25)
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Anti-EPCR Antibody (2F25)

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Anti-EPCR Antibody (2F25)
产品编号 TMAY-03823 别名 protein C receptor, endothelial

Anti-EPCR Antibody (2F25) 是一种 Rabbit 抗体,靶向 EPCR。Anti-EPCR Antibody (2F25) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,289
5日内发货
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产品介绍

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产品描述
Anti-EPCR Antibody (2F25) is a Rabbit antibody targeting EPCR. Anti-EPCR Antibody (2F25) can be used in ELISA.
别名protein C receptor, endothelial
Ig Type
Rabbit IgG
克隆号
2F25
交叉反应
Rat
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Rat Epcr / PROCR (rR Epcr / PROCR; TMPY-03347; ; Met1-Ser213).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Endothelial protein C receptor (EPCR), also known as activated protein C receptor (APC receptor) or PROCR, is a receptor for Protein C. Protein C plays an important role in many metabolism processes in humans and other animals after activated by binding to Endothelial protein C receptor (EPCR). Because of the EPCR is found primarily on endothelial cells (cells on the inside of blood vessels), activated protein C is found mainly near endothelial cells. Protein C is pleiotropic, with two main functions: anticoagulation and cytoprotection. Which function will be performed depending on whether or not protein C remains bind to EPCR after activated. The anticoagulation occurs when it does not. In this case, protein C functions as an anticoagulant by irreversibly proteolytically inactivating Factor Va and Factor VIIIa, turning them into Factor Vi and Factor VIIIi respectively. When still bound to EPCR, activated protein C performs its cytoprotective effects, acting on the effector substrate PAR-1, protease-activated receptor-1. To a degree, APC's anticoagulant properties are independent of its cytoprotective ones, in that expression of one pathway is not affected by the existence of the other.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Rat Epcr / PROCR Protein (TMPY-03347)
抗原种属
Rat
研究领域
Serine Proteases and Regulators
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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