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别名 P-selectin, PADGEM, Leukocyte-endothelial cell adhesion molecule 3, LECAM3, Granule membrane protein 140, GMP-140, CD62 antigen-like family member P
Anti-P-selectin Polyclonal Antibody 是一种 Rabbit 抗体,靶向 P-selectin。Anti-P-selectin Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P,WB。
Anti-P-selectin Polyclonal Antibody 是一种 Rabbit 抗体,靶向 P-selectin。Anti-P-selectin Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P,WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
| 产品描述 | Anti-P-selectin Polyclonal Antibody is a Rabbit antibody targeting P-selectin. Anti-P-selectin Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB. |
| 别名 | P-selectin, PADGEM, Leukocyte-endothelial cell adhesion molecule 3, LECAM3, Granule membrane protein 140, GMP-140, CD62 antigen-like family member P |
| Ig Type | IgG |
| 反应种属 | Human,Mouse,Rat |
| 验证活性 | 1. Paraformaldehyde-fixed, paraffin embedded Rat Spleen; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CD62p Polyclonal Antibody, Unconjugated (TMAB-01587) at 1:100 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 2. Paraformaldehyde-fixed, paraffin embedded Human Spleen; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CD62p Polyclonal Antibody, Unconjugated (TMAB-01587) at 1:100 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 3. Paraformaldehyde-fixed, paraffin embedded Human Colon Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CD62p Polyclonal Antibody, Unconjugated (TMAB-01587) at 1:100 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 4. Paraformaldehyde-fixed, paraffin embedded Human Tonsil; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CD62p Polyclonal Antibody, Unconjugated (TMAB-01587) at 1:100 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 5. Paraformaldehyde-fixed, paraffin embedded Human Lung; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CD62p Polyclonal Antibody, Unconjugated (TMAB-01587) at 1:100 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 6. Paraformaldehyde-fixed, paraffin embedded Human Colon; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CD62p Polyclonal Antibody, Unconjugated (TMAB-01587) at 1:100 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 7. Paraformaldehyde-fixed, paraffin embedded Human Esophagus; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CD62p Polyclonal Antibody, Unconjugated (TMAB-01587) at 1:100 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
| 应用 | IFIHC-FrIHC-PWB |
| 推荐剂量 | WB: 1:500-1000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 组织特异性 | Stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 研究背景 | This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. [provided by RefSeq, Jul 2008] |
| 免疫原 | KLH conjugated synthetic peptide: mouse P-selectin |
| 抗原种属 | Mouse |
| 基因名称 | SELP |
| 基因ID | |
| 蛋白名称 | P-selectin |
| Uniprot ID | |
| 研究领域 | Endothelial Cell Markers,Cell adhesion molecules,Platelets,Regulatory T Cells,Platelets,Thrombocytic Lineage |
| 功能 | Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1. |
| 分子量 | Theoretical: 88 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | store at -20°C |