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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CD43 Polyclonal Antibody

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货号 TMAB-03986

Anti-CD43 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CD43。Anti-CD43 Polyclonal Antibody 可用于 WB。

Anti-CD43 Polyclonal Antibody

Anti-CD43 Polyclonal Antibody

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货号 TMAB-03986

Anti-CD43 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CD43。Anti-CD43 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-CD43 Polyclonal Antibody is a Rabbit antibody targeting CD43. Anti-CD43 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse,Rat
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein.
组织特异性Cell surface of thymocytes, T-lymphocytes, neutrophils, plasma cells and myelomas.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
浓度1mg/ml
研究背景This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017]
抗原信息
免疫原
KLH conjugated synthetic peptide: human CD43
抗原种属
Human
基因名称
SPN
基因ID
6693
蛋白名称
Leukosialin
Uniprot ID
P16150
功能
One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1. During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response.
化学信息
分子量Theoretical: 38 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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