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- 3550个临床期化合物集合，可用于高通量筛选和高内涵筛选；
- 所有化合物均已被批准进入临床期，按临床一期、二期、三期等进行分类；
- 是老药新用和细胞诱导的有效工具
- 详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
- 结构多样，药效显著，可渗透细胞；
- NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。
临床期小分子药物库
Clinical Compound Library
很棒临床期小分子药物库汇集了3550 个已经进入临床实验的化合物，这些化合物经过大量的临床前研究实验，具有活性高、毒性低和机制明确的特点。我们随货信息中每个化合物都包含了其作用靶点、临床期、适应症等信息，涉及癌症、炎症、感染、神经病、心血管病和消化系统疾病等多种热门病症，以及JAK、EGFR、mTOR、CDK、HDAC、AKt、PARP 等众多成药靶点，适用于药物筛选的同时，也是细胞诱导分化的有力工具。
TargetMol 的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。
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化合物库相关信息
Excel
SDF
联系我们获取更多批次信息产品编号 L3400
临床期小分子药物库规格
- 1 mg
- 30 μL x 10 mM (in DMSO)
- 50 μL x 10 mM (in DMSO)
- 100 μL x 10 mM (in DMSO)
- 250 μL x 10 mM (in DMSO)
询价 & 定制
产品描述
包装和储存
- 可选用DMSO耐受的96/384孔板或2D 条形码编码管；
- 干粉蓝冰运输，DMSO溶液干冰运输；
- 排布：96孔板：1st & 12th 空白对照，384孔板：1st & 2nd & 23th & 24th空白对照。
SCI 文献
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化合物库组成
Autophagy
Apoptosis
Antibacterial
Antibiotic
Endogenous Metabolite
5-HT Receptor
Adrenergic Receptor
DNA/RNA Synthesis
HIV Protease
AChR
Dopamine Receptor
COX
Histamine Receptor
VEGFR
Sodium Channel
Parasite
Potassium Channel
EGFR
Calcium Channel
PI3K
PDE
Antifungal
Topoisomerase
FLT
CDK
HCV Protease
Cytochromes P450
Dehydrogenase
PDGFR
JAK
SARS-CoV
Microtubule Associated
PPAR
Reactive Oxygen Species
FGFR
c-Kit
Glucocorticoid Receptor
Ferroptosis
HDAC
mTOR
Influenza Virus
c-Met/HGFR
GABA Receptor
Src
HBV
NF-κB
Estrogen/progestogen Receptor
Mitophagy
Prostaglandin Receptor
Reverse Transcriptase
RAAS
Tyrosine Kinases
GPCR
Adenosine Receptor
Nucleoside Antimetabolite/Analog
Bcr-Abl
Raf
Androgen Receptor
iGluR
Proteasome
NMDAR
Serotonin Transporter
Phosphatase
GluR
Epigenetic Reader Domain
Akt
Virus Protease
PARP
TRP/TRPV Channel
ROS
HSV
Aurora Kinase
Transferase
Norepinephrine
Beta Amyloid
p38 MAPK
Estrogen Receptor/ERR
HSP
Progesterone Receptor
ALK
MEK
HIF/HIF Prolyl-Hydroxylase
ATPase
Opioid Receptor
IL Receptor
Antiviral
c-RET
TNF
Histone Methyltransferase
DPP-4
Cholinesterase (ChE)
P-gp
HER
Carbonic Anhydrase
Antioxidant
ERK
Antifection
TLR
Trk receptor
GSK-3
PKC
MAO
Endothelin Receptor
MMP
c-Fms
ribosome
DNA Alkylator/Crosslinker
CCR
CXCR
Chk
Interleukin
Bcl-2 Family
Retinoid Receptor
Thrombin
S1P Receptor
E1/E2/E3 Enzyme
Gamma-secretase
Mitochondrial Metabolism
AMPK
Syk
TAM Receptor
p53
Thyroid hormone receptor(THR)
Proton pump
DNA-PK
Integrin
LPL Receptor
Caspase
SGLT
STAT
Phospholipase
HIF
CFTR
NO Synthase
Wnt/beta-catenin
Antifolate
Guanylate cyclase
Nrf2
Neurokinin receptor
FAK
NADPH
CSF-1R
P2X Receptor
DNA Alkylation
Hedgehog/Smoothened
PLK
BTK
DHFR
P2Y Receptor
Reductase
CETP
Glutathione Peroxidase
MRP
GNRH Receptor
ROCK
IAP
Vasopressin Receptor
OX Receptor
Lipoxygenase
IGF-1R
TGF-beta/Smad
RSV
ATM/ATR
Hydroxylase
Cannabinoid Receptor
HMG-CoA Reductase
S6 Kinase
ROS Kinase
Monoamine Oxidase
Mdm2
PKA
Indoleamine 2,3-Dioxygenase (IDO)
Histone Demethylase
JNK
Factor Xa
Pim
Serine Protease
FXR
Aryl Hydrocarbon Receptor
RIP kinase
Drug Metabolite
Glucosidase
Smo
Xanthine Oxidase
DNA
Beta-Secretase
Sirtuin
Casein Kinase
Ligand for E3 Ligase
DNA Methyltransferase
Sigma receptor
ADC Cytotoxin
ROR
Amino Acids and Derivatives
BACE
Glucokinase
Glucagon Receptor
Isocitrate Dehydrogenase (IDH)
PAK
Bradykinin Receptor
Aminopeptidase
IκB/IKK
IRAK
AhR
Kinesin
NOS
Leukotriene Receptor
IDO
MT Receptor
Molecular Glues
Fatty Acid Synthase
Acyltransferase
Ephrin Receptor
CRFR
GHSR
Complement System
Gap Junction Protein
Ras
Chloride channel
PROTACs
CRM1
DprE1
YAP
LTR
IFNAR
Tie-2
Melatonin Receptor
Cholecystokinin Receptor
Liver X Receptor
Cysteine Protease
DNA gyrase
GlyT
Monoamine Transporter
Neuropeptide Y Receptor
FAAH
CaMK
Wee1
PGE Synthase
MAPK
OAT
Decarboxylase
Neprilysin
Acetyl-CoA Carboxylase
Melanocortin Receptor
CGRP Receptor
NADPH-oxidase
Kras
NEDD8
Arginase
Cell wall
PERK
CaSR
Rho
NAMPT
PYK2
Glutaminase
Myosin
Annexin A
UGT
ABC Transporter
Somatostatin
KSP
DUB
Telomerase
STING
Free radical scavengers
GPCR19
LPA Receptor
PDK
Adenosine Deaminase
NOD
Tyrosinase
Protease-activated Receptor
NOD-like Receptor (NLR)
Imidazoline Receptor
PD-1/PD-L1
Taste receptor
GSNOR
Ligands for Target Protein for PROTAC
DYRK
VDA
Galectin
Serine/threonin kinase
IRE1
LDL
Na-K-Cl cotransporter
Hexokinase
Integrase
HCN Channel
Stearoyl-CoA Desaturase (SCD)
Epoxide Hydrolase
ATP Citrate Lyase
BCRP
Porcupine
CD73
transporter
PAI-1
GST
Oxytocin Receptor
Discoidin Domain Receptor (DDR)
p97
MLK
Apelin receptor
Advanced Glycation End Products
Adenylyl Cyclase
MicroRNA
NPC1L1
Monocarboxylate transporter
Hydrogenase
RAR/RXR
MALT
Arrestin
Lipase
TOPK
GTPase
c-Myc
N-Acetylglucosaminyltransferase
AAK1
VDAC
Hck
Neurotensin Receptor
Stemness kinase
SIK
FLAP
PAFR
Fas/FasL
GRK
Phosphorylase
Anion Exchanger
PROTAC Linker
Thioredoxin
ACK1
Lipid
Huntingtin
PSMA
MNK
Survivin
Histone Acetyltransferase
GluCls
ASK
Pyroptosis
MELK
Methionine Adenosyltransferase (MAT)
Hippo pathway
Aromatase
PI4K
KLF
CRISPR/Cas9
Aquaporin
RXFP receptor
SGK
Anti-infection
BMI-1
PKM
Vitamin
Drug-Linker Conjugates for ADC
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