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- 3404个临床期化合物集合，可用于高通量筛选和高内涵筛选；
- 所有化合物均已被批准进入临床期，按临床一期、二期、三期等进行分类；
- 是老药新用和细胞诱导的有效工具
- 详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
- 结构多样，药效显著，可渗透细胞；
- NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。
临床期小分子药物库
Clinical Compound Library
很棒临床期小分子药物库汇集了3404 个已经进入临床实验的化合物，这些化合物经过大量的临床前研究实验，具有活性高、毒性低和机制明确的特点。我们随货信息中每个化合物都包含了其作用靶点、临床期、适应症等信息，涉及癌症、炎症、感染、神经病、心血管病和消化系统疾病等多种热门病症，以及JAK、EGFR、mTOR、CDK、HDAC、AKt、PARP 等众多成药靶点，适用于药物筛选的同时，也是细胞诱导分化的有力工具。
TargetMol 的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。
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化合物库相关信息
Excel
SDF
联系我们获取更多批次信息产品编号 L3400
临床期小分子药物库规格
- 1 mg
- 30 μL x 10 mM (in DMSO)
- 50 μL x 10 mM (in DMSO)
- 100 μL x 10 mM (in DMSO)
- 250 μL x 10 mM (in DMSO)
询价 & 定制
产品描述
包装和储存
- 可选用DMSO耐受的96/384孔板或2D 条形码编码管；
- 干粉蓝冰运输，DMSO溶液干冰运输；
- 排布：96孔板：1st & 12th 空白对照，384孔板：1st & 2nd & 23th & 24th空白对照。
SCI 文献
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化合物库组成
Autophagy
Apoptosis
Antibacterial
Antibiotic
Endogenous Metabolite
5-HT Receptor
Adrenergic Receptor
DNA/RNA Synthesis
AChR
HIV Protease
Dopamine Receptor
COX
Histamine Receptor
VEGFR
Parasite
Sodium Channel
Calcium Channel
EGFR
PI3K
Antifungal
Potassium Channel
PDE
Topoisomerase
FLT
HCV Protease
CDK
Cytochromes P450
PDGFR
Dehydrogenase
JAK
Microtubule Associated
Reactive Oxygen Species
SARS-CoV
PPAR
FGFR
Glucocorticoid Receptor
c-Kit
mTOR
Ferroptosis
HDAC
Influenza Virus
c-Met/HGFR
Src
Estrogen/progestogen Receptor
GABA Receptor
RAAS
HBV
NF-κB
Mitophagy
Prostaglandin Receptor
Reverse Transcriptase
Nucleoside Antimetabolite/Analog
Tyrosine Kinases
GPR
Adenosine Receptor
Bcr-Abl
Raf
Proteasome
Androgen Receptor
iGluR
Serotonin Transporter
Epigenetic Reader Domain
Aurora Kinase
Akt
Phosphatase
Virus Protease
TRP/TRPV Channel
ROS
HSV
HER
Progesterone Receptor
Transferase
p38 MAPK
Estrogen Receptor/ERR
PARP
GluR
Norepinephrine
Opioid Receptor
Beta Amyloid
MEK
ALK
NMDAR
IL Receptor
HSP
TNF
c-RET
HIF/HIF Prolyl-Hydroxylase
ATPase
DPP-4
P-gp
Trk receptor
Carbonic Anhydrase
Antioxidant
Antifection
Cholinesterase (ChE)
Antiviral
Histone Methyltransferase
GSK-3
ERK
CXCR
c-Fms
ribosome
DNA Alkylator/Crosslinker
Mitochondrial Metabolism
PKC
Gamma-secretase
Interleukin
TLR
Endothelin Receptor
Retinoid Receptor
Thrombin
S1P Receptor
Proton pump
MAO
MMP
Chk
Bcl-2 Family
CCR
Phospholipase
DNA-PK
LPL Receptor
Thyroid hormone receptor(THR)
E1/E2/E3 Enzyme
SGLT
AMPK
CFTR
NO Synthase
STAT
HIF
Syk
p53
Caspase
Guanylate cyclase
TAM Receptor
NADPH
Integrin
Wnt/beta-catenin
Antifolate
CSF-1R
DNA Alkylation
Hedgehog/Smoothened
IGF-1R
Nrf2
Neurokinin receptor
FAK
Glutathione Peroxidase
Mdm2
CETP
PKA
MRP
P2X Receptor
Lipoxygenase
TGF-beta/Smad
Hydroxylase
PLK
Cannabinoid Receptor
Monoamine Oxidase
BTK
P2Y Receptor
Reductase
GNRH Receptor
ROCK
IAP
Drug Metabolite
Vasopressin Receptor
Indoleamine 2,3-Dioxygenase (IDO)
ATM/ATR
HMG-CoA Reductase
RSV
S6 Kinase
ROS Kinase
ADC Cytotoxin
DHFR
JNK
Histone Demethylase
Serine Protease
RIP kinase
FXR
Aryl Hydrocarbon Receptor
Glucosidase
Smo
Xanthine Oxidase
DNA
Beta-Secretase
Sirtuin
OX Receptor
Aminopeptidase
Casein Kinase
Sigma receptor
ROR
BACE
Amino Acids and Derivatives
Glucokinase
Pim
Leukotriene Receptor
Glucagon Receptor
Bradykinin Receptor
Isocitrate Dehydrogenase (IDH)
PAK
IκB/IKK
IRAK
AhR
DNA Methyltransferase
Kinesin
Tie-2
Factor Xa
IDO
DNA gyrase
Fatty Acid Synthase
Acyltransferase
Ephrin Receptor
Ligand for E3 Ligase
Complement System
Chloride channel
NOS
Melatonin Receptor
DprE1
YAP
LTR
IFNAR
Cholecystokinin Receptor
Liver X Receptor
MT Receptor
Monoamine Transporter
Neuropeptide Y Receptor
CaMK
PGE Synthase
Decarboxylase
Molecular Glues
FAAH
Wee1
OAT
Neprilysin
Acetyl-CoA Carboxylase
CGRP Receptor
CRFR
Melanocortin Receptor
GHSR
Gap Junction Protein
NADPH-oxidase
CRM1
Arginase
Cell wall
CaSR
PYK2
Myosin
Annexin A
Rho
Cysteine Protease
NAMPT
ABC Transporter
GlyT
Somatostatin
KSP
DUB
STING
Free radical scavengers
GPCR19
Telomerase
MAPK
LPA Receptor
PDK
Protease-activated Receptor
Adenosine Deaminase
Ras
Tyrosinase
NOD-like Receptor (NLR)
Imidazoline Receptor
PD-1/PD-L1
Kras
Taste receptor
PROTACs
GSNOR
NEDD8
Ligands for Target Protein for PROTAC
PERK
VDA
Galectin
Serine/threonin kinase
IRE1
UGT
LDL
Na-K-Cl cotransporter
Hexokinase
HCN Channel
Stearoyl-CoA Desaturase (SCD)
ATP Citrate Lyase
BCRP
transporter
Integrase
Epoxide Hydrolase
Porcupine
CD73
GST
p97
MLK
PAI-1
Oxytocin Receptor
Discoidin Domain Receptor (DDR)
Adenylyl Cyclase
Monocarboxylate transporter
MALT
Arrestin
DYRK
GTPase
c-Myc
Advanced Glycation End Products
MicroRNA
NPC1L1
Hydrogenase
RAR/RXR
Lipase
AAK1
Stemness kinase
Fas/FasL
Phosphorylase
Anion Exchanger
N-Acetylglucosaminyltransferase
VDAC
Hck
Glutaminase
FLAP
PAFR
GRK
ACK1
PSMA
PROTAC Linker
Thioredoxin
Lipid
MNK
Survivin
Histone Acetyltransferase
GluCls
Pyroptosis
Methionine Adenosyltransferase (MAT)
KLF
PI4K
SGK
PKM
ASK
MELK
Hippo pathway
Aromatase
CRISPR/Cas9
Aquaporin
RXFP receptor
Anti-infection
BMI-1
NOD
Vitamin
Drug-Linker Conjugates for ADC
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