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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-BARD1 Polyclonal Antibody

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货号 TMAB-03025

Anti-BARD1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 BARD1。Anti-BARD1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。

Anti-BARD1 Polyclonal Antibody

Anti-BARD1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-03025

Anti-BARD1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 BARD1。Anti-BARD1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-BARD1 Polyclonal Antibody is a Rabbit antibody targeting BARD1. Anti-BARD1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Chicken,Dog,Pig,Cow,Horse)
应用IHC-PIHC-FrIFFCM
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景BRCA1 Associated RING Domain gene 1 (BARD1) interacts with the N terminal region of BRCA1. In addition to its ability to bind BRCA1 in vivo and in vitro, BARD1 shares homology with the 2 most conserved regions of BRCA1: the N terminal RING motif and the C terminal BRCT domain. The RING motif is a cysteine rich sequence found in a variety of proteins that regulate cell growth, including the products of tumor suppressor genes and dominant protooncogenes. The BARD1 protein also contains 3 tandem ankyrin repeats. The BARD1/BRCA1 interaction is disrupted by tumorigenic amino acid substitutions in BRCA1, implying that the formation of a stable complex between these proteins may be an essential aspect of BRCA1 tumor suppression. BARD1 may be the target of oncogenic mutations in breast or ovarian cancer. BARD1 also plays a role in mediating apoptotic stress and p53 dependent.
抗原信息
免疫原
KLH conjugated synthetic peptide: human BARD1
抗原种属
Human
基因名称
BARD1
基因ID
580
蛋白名称
BRCA1-associated RING domain protein 1
Uniprot ID
Q99728
化学信息
分子量Theoretical: 85 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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