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Anti-AIF Polyclonal Antibody
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产品编号 TMAB-00082
Anti-AIF Polyclonal Antibody 是一种 Rabbit 抗体，靶向 AIF。Anti-AIF Polyclonal Antibody 可用于 WB。
Anti-AIF Polyclonal Antibody
Anti-AIF Polyclonal Antibody
还可以产品编号 TMAB-00082
Anti-AIF Polyclonal Antibody 是一种 Rabbit 抗体，靶向 AIF。Anti-AIF Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
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产品介绍
生物活性
抗原信息
| 产品描述 | Anti-AIF Polyclonal Antibody is a Rabbit antibody targeting AIF. Anti-AIF Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat,Pig (predicted:Chicken,Dog,Cow,Rabbit,Sheep) |
| 验证活性 | 1. Sample: Lane 1: K562 (Human) Cell Lysate at 30 μg Lane 2: Testis (Rat) Lysate at 40 μg Lane 3: Testis (Mouse) Lysate at 40 μg Primary: Anti-AIF (TMAB-00082) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 67/62/57 kDa Observed band size: 62 kDa 2. Sample: Liver (Mouse) Lysate at 40 μg Primary: Anti-AIF at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 57 kDa Observed band size: 63 kDa |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Mitochondrion intermembrane space. Mitochondrion inner membrane. Cytoplasm. Nucleus. Cytoplasm, perinuclear region. Note=Proteolytic cleavage during or just after translocation into the mitochondrial intermembrane space (IMS) results in the formation of an inner-membrane-anchored mature form (AIFmit). During apoptosis, further proteolytic processing leads to a mature form, which is confined to the mitochondrial IMS in a soluble form (AIFsol). AIFsol is released to the cytoplasm in response to specific death signals, and translocated to the nucleus, where it induces nuclear apoptosis. Colocalizes with EIF3G in the nucleus and perinuclear region. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究背景 | This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10. [provided by RefSeq, May 2010]. |
| 免疫原 | KLH conjugated synthetic peptide: human AIF |
| 抗原种属 | Human |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Metabolism,Chromatin condensation,Chromatin condensation,Chromatin Condensation,Nuclear,Apoptosis,Oxidative stress |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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