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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-BRN3B Polyclonal Antibody

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货号 TMAB-03223

Anti-BRN3B Polyclonal Antibody 是一种 Rabbit 抗体，靶向 BRN3B。Anti-BRN3B Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。

Anti-BRN3B Polyclonal Antibody

Anti-BRN3B Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-03223

Anti-BRN3B Polyclonal Antibody 是一种 Rabbit 抗体，靶向 BRN3B。Anti-BRN3B Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-BRN3B Polyclonal Antibody is a Rabbit antibody targeting BRN3B. Anti-BRN3B Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Dog,Pig,Cow,Horse,Sheep)
应用IHC-PIHC-FrIFFCM
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus speckle.
组织特异性Brain. Seems to be specific to the retina.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The Brn family of transcription factors are found in a highly restricted subset of neurons and are critical to the early embryonic development of the central nervous system. Brn-1 and Brn-2 are class III POU (Pit-Oct-Unc) domain proteins, whereas Brn-3 is a class IV POU domain protein. Three Brn-3 proteins have been described and are designated Brn-3a, Brn-3b and Brn-3c. While Brn-3a and Brn-3c stimulate transcription, Brn-3b generally functions as a transcriptional repressor. However, Brn-3b, but not Brn-3a, has been shown to regulate the expression of the acetylcholine receptor. Interestingly, Brn-3a has two functional transactivating domains, one at the amino-terminus and one at the carboxy-terminus. Brn-2 is thought to be involved in smooth muscle cell development and differentiation.
抗原信息
免疫原
KLH conjugated synthetic peptide: human BRN3B
抗原种属
Human
基因名称
POU4F2
基因ID
5458
蛋白名称
POU domain, class 4, transcription factor 2
Uniprot ID
Q12837.2
功能
Transcription factor. May play a role in determining or maintaining the identities of a small subset of visual system neurons.
化学信息
分子量Theoretical: 41 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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