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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-MARCH5 Polyclonal Antibody

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货号 TMAB-08609

Anti-MARCH5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 MARCH5。Anti-MARCH5 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-MARCH5 Polyclonal Antibody

Anti-MARCH5 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-08609

Anti-MARCH5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 MARCH5。Anti-MARCH5 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-MARCH5 Polyclonal Antibody is a Rabbit antibody targeting MARCH5. Anti-MARCH5 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Chicken,Dog,Cow)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:50-200
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Mitochondrion outer membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane. Note=Authors show that the protein can be detected in endoplasmic reticulum (PubMed:14722266). Authors (PubMed:16874301) show its presence only in mitochondria (PubMed:16874301).
组织特异性Expressed in brain, heart, liver, lung, spleen, stomach, testis, skeletal and muscle.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景MARCH5 is a member of the E3 ubiquitin-protein ligase family. This mitochonrial E3 ubiquitin-protein ligase plays an importnat role in controlling the morphology of the mitochondria. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. MARCH5 has been shown to interact with MTFN2 and ubiquitinated forms of DRP1.
抗原信息
免疫原
KLH conjugated synthetic peptide: human MARCH5
抗原种属
Human
基因名称
MARCHF5
基因ID
54708
蛋白名称
E3 ubiquitin-protein ligase MARCHF5
Uniprot ID
Q9NX47
功能
Mitochondrial E3 ubiquitin-protein ligase that plays a crucial role in the control of mitochondrial morphology by acting as a positive regulator of mitochondrial fission. May play a role in the prevention of cell senescence acting as a regulator of mitochondrial quality control. Promotes ubiquitination of FIS1, DNM1L and MFN1.
化学信息
分子量Theoretical: 31 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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