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Anti-DAP12 Antibody (2G400)
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产品编号 TMAC-01104
别名 TYRO protein tyrosine kinase binding protein, TYOBP, PLOSL, Killer-activating receptor-associated protein, KAR-associated protein, KARAP, DNAX-activation protein 12, DAP12, DAP 12
Anti-DAP12 Antibody (2G400) 是一种 Rabbit 抗体，靶向 DAP12。Anti-DAP12 Antibody (2G400) 可用于 WB,IHC,FCM。
Anti-DAP12 Antibody (2G400)
Anti-DAP12 Antibody (2G400)
还可以产品编号 TMAC-01104 别名 TYRO protein tyrosine kinase binding protein, TYOBP, PLOSL, Killer-activating receptor-associated protein, KAR-associated protein, KARAP, DNAX-activation protein 12, DAP12, DAP 12
Anti-DAP12 Antibody (2G400) 是一种 Rabbit 抗体，靶向 DAP12。Anti-DAP12 Antibody (2G400) 可用于 WB,IHC,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,490 | 5日内发货 | |
| 100 μL | ¥ 2,490 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-DAP12 Antibody (2G400) is a Rabbit antibody targeting DAP12. Anti-DAP12 Antibody (2G400) can be used in WB,IHC,FCM. |
| 别名 | TYRO protein tyrosine kinase binding protein, TYOBP, PLOSL, Killer-activating receptor-associated protein, KAR-associated protein, KARAP, DNAX-activation protein 12, DAP12, DAP 12 |
| Ig Type | IgG |
| 交叉反应 | Human |
| 验证活性 | 1. Western blot analysis of DAP12 on THP-1 cell using anti-DAP12 antibody at 1/500 dilution. 2. Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-DAP12 antibody. Counter stained with hematoxylin. 3. Flow cytometric analysis of K562 cells with DAP12 antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody. |
| 应用 | |
| 推荐剂量 | WB: 1:500-1000; IHC: 1:50-200; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Natural killer (NK) cells are regulated by stimulatory and inhibitory signals from a variety of receptors. Three main receptor families are responsible for NK cells recognition of MHC I molecules, including Ly-49, CD94/NKG2 and KIR (killer-cell inhibitory receptor). DAP12 is a phosphoprotein that is involved in the activation of NK cells. This protein interacts with membrane glycoproteins of the KIR family, resulting in cellular activation. DAP12 also binds to CD94/NKG2C, an activating NK cell receptor belonging to the C-type lectin superfamily. Additional proteins that bind to DAP12 include Ly-49D and Ly-49H, which associate with DAP12 in the plasma membrane. Phosphorylated DAP12 binds to ZAP-70 and Syk, suggesting that the activation pathway may be similar to that of the T and B cell antigen receptors. |
| 偶联 | Unconjugated |
| 免疫原 | A synthesized peptide: within human DAP12 aa 60-100 |
| 抗原种属 | human |
| Uniprot ID |
| 分子量 | Theoretical: 12 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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