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Anti-MRP2 Antibody (3I477)

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货号 TMAB-08996

Anti-MRP2 Antibody (3I477) 是一种 Rabbit 抗体，靶向 MRP2。Anti-MRP2 Antibody (3I477) 可用于 FCM, IHC-P, IHC-Fr, IF。

Anti-MRP2 Antibody (3I477)

Anti-MRP2 Antibody (3I477)

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Rating icon 还可以
货号 TMAB-08996

Anti-MRP2 Antibody (3I477) 是一种 Rabbit 抗体，靶向 MRP2。Anti-MRP2 Antibody (3I477) 可用于 FCM, IHC-P, IHC-Fr, IF。

规格价格库存数量
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,480
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
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产品介绍

生物活性
产品描述
Anti-MRP2 Antibody (3I477) is a Rabbit antibody targeting MRP2. Anti-MRP2 Antibody (3I477) can be used in FCM, IHC-P, IHC-Fr, IF.
Ig Type
IgG
克隆号
3I477
反应种属
Human
应用FCMIHC-PIHC-FrIF
推荐剂量
FCM: 1μg/Test; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Membrane; Multi-pass membrane protein.
组织特异性Found on the apical membrane of polarized cells in liver, kidney and intestine. The highest expression is found in liver.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景multidrug resistance-associated protein 2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. Belongs to the ABC transporter family.
抗原信息
免疫原
A synthesized peptide: human ABCC2
抗原种属
Human
基因名称
ABCC2
基因ID
1244
蛋白名称
Canalicular multispecific organic anion transporter 1
Uniprot ID
Q92887
功能
Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter.
化学信息
分子量Theoretical: 174 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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