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顶部生物活性储存和溶解信息计算器

Anti-Phospho-CAMKII beta/gamma/delta (Thr287) Polyclonal Antibody

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Anti-Phospho-CAMKII beta/gamma/delta (Thr287) Polyclonal Antibody
产品编号 TMAC-00536
别名 p-CAMKII beta/gamma/delta (Thr287), p-CAMKII beta/gamma/delta (T287), CAMKII beta/gamma/delta (p-Thr287), CAMKII beta/gamma/delta (p-T287)

Anti-Phospho-CAMKII beta/gamma/delta (Thr287) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-CAMKII beta/gamma/delta (Thr287)。Anti-Phospho-CAMKII beta/gamma/delta (Thr287) Polyclonal Antibody 可用于 IF,WB,IHC,ELISA。

Anti-Phospho-CAMKII beta/gamma/delta (Thr287) Polyclonal Antibody

Anti-Phospho-CAMKII beta/gamma/delta (Thr287) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-CAMKII beta/gamma/delta (Thr287) Polyclonal Antibody
产品编号 TMAC-00536 别名 p-CAMKII beta/gamma/delta (Thr287), p-CAMKII beta/gamma/delta (T287), CAMKII beta/gamma/delta (p-Thr287), CAMKII beta/gamma/delta (p-T287)

Anti-Phospho-CAMKII beta/gamma/delta (Thr287) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-CAMKII beta/gamma/delta (Thr287)。Anti-Phospho-CAMKII beta/gamma/delta (Thr287) Polyclonal Antibody 可用于 IF,WB,IHC,ELISA。

规格价格库存数量
100 μL
¥ 2,240
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-CAMKII beta/gamma/delta (Thr287) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CAMKII beta/gamma/delta (Thr287). Anti-Phospho-CAMKII beta/gamma/delta (Thr287) Polyclonal Antibody can be used in IF,WB,IHC,ELISA.
别名p-CAMKII beta/gamma/delta (Thr287), p-CAMKII beta/gamma/delta (T287), CAMKII beta/gamma/delta (p-Thr287), CAMKII beta/gamma/delta (p-T287)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of extracts from Rat brain using CaMK2-beta/gamma/delta (Phospho-Thr287) Antibody TMAC-00536. The lane on the right is treated with the antigen-specific peptide.
应用
IF
WB
IHC
ELISA
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca2+ transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner. This structural function is required for correct targeting of CaMK2A, which acts downstream of NMDAR to promote dendritic spine and synapse formation and maintain synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. In developing hippocampal neurons, promotes arborization of the dendritic tree and in mature neurons, promotes dendritic remodeling. Participates in the modulation of skeletal muscle function in response to exercise. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca2+ transport and in fast-twitch muscle participates in the control of Ca2+ release from the SR through phosphorylation of triadin, a ryanodine receptor-coupling factor, and phospholamban (PLN/PLB), an endogenous inhibitor of SERCA2A/ATP2A2.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of Threonine 287 (Q-E-T(p)-V-E) derived from Human CaMK2- beta/ gamma/ delta
抗原种属
human
Uniprot ID
Q13554 & Q13555 & Q13557
化学信息
分子量Actual: 50 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

pCAMKII beta/gamma/delta (Thr287)pCAMKII beta/gamma/delta (T287)CAMKII beta/gamma/delta (pThr287)CAMKII beta/gamma/delta (pT287)CAMKII beta/gamma/delta (phospho-Thr287)CAMKII beta/gamma/delta (phospho-T287)

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