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Anti-OSTM1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 OSTM1。Anti-OSTM1 Polyclonal Antibody 可用于 WB,FCM。
Anti-OSTM1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 OSTM1。Anti-OSTM1 Polyclonal Antibody 可用于 WB,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-OSTM1 Polyclonal Antibody is a Rabbit antibody targeting OSTM1. Anti-OSTM1 Polyclonal Antibody can be used in WB,FCM. |
| Ig Type | IgG |
| 反应种属 | Human,Mouse,Rat (predicted:Pig) |
| 应用 | WBFCM |
| 推荐剂量 | WB: 1:500-2000; FCM: 1μg/Test |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | OSTM1 (osteopetrosis associated transmembrane protein 1), also known as gl (gray-lethal) or HSPC019, is a 338 amino acid single-pass type I membrane protein that is expressed primarily in osteoclasts and melanocytes as well as brain, kidney and spleen. Bone autosomal recessive osteopetrosis (ARO) is the most severe form of hereditary bone disease whose cellular basis is in the osteoclast and is characterized by abnormally dense bone, due to defective resorption of immature bone. ARO is suggested to be caused by mutations in the OSTM1 gene. The disorder occurs in two forms: a severe autosomal recessive form occurring in utero, infancy, or childhood, and a benign autosomal dominant form occurring in adolescence or adulthood. Defects in the OSTM1 gene are also the cause of the spontaneous gl mutant, which is responsible for a coat color defect in mice. |
| 免疫原 | KLH conjugated synthetic peptide: human OSTM1 |
| 抗原种属 | Human |
| 基因名称 | OSTM1 |
| 基因ID | |
| 蛋白名称 | Osteopetrosis-associated transmembrane protein 1 |
| Uniprot ID | |
| 功能 | Required for osteoclast and melanocyte maturation and function (By similarity). |
| 分子量 | Theoretical: 33 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |