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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-OSTM1 Polyclonal Antibody

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货号 TMAB-09826

Anti-OSTM1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 OSTM1。Anti-OSTM1 Polyclonal Antibody 可用于 WB,FCM。

Anti-OSTM1 Polyclonal Antibody

Anti-OSTM1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-09826

Anti-OSTM1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 OSTM1。Anti-OSTM1 Polyclonal Antibody 可用于 WB,FCM。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-OSTM1 Polyclonal Antibody is a Rabbit antibody targeting OSTM1. Anti-OSTM1 Polyclonal Antibody can be used in WB,FCM.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Pig)
验证活性
1. Positive control: mouse Splenocytes (2% Paraformaldehyde-fixed)
Isotype Control Antibody: Rabbit IgG; Dilution: 1 μg in 100 μl 1 X PBS containing 0.5% BSA
Secondary Antibody: Goat anti-rabbit IgG-FITC;
Dilution: 1: 200 in 1 X PBS containing 0.5% BSA
Primary Antibody: Rabbit Anti-OSTM1 (TMAB-09826);
Dilution: 1 μg in 100 μl 1X PBS containing 0.5% BSA
2. Sample:
Lane 1: Mouse Spleen tissue lysates
Lane 2: Mouse Lung tissue lysates
Lane 3: Rat Liver tissue lysates
Lane 4: Rat Spleen tissue lysates
Lane 5: Human U87MG cell lysates
Lane 6: Human U251 cell lysates
Lane 7: Human THP-1 cell lysates
Primary: Anti-OSTM1 (TMAB-09826) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 33 kD
Observed band size: 35 kD
应用WBFCM
推荐剂量
WB: 1:500-2000; FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景OSTM1 (osteopetrosis associated transmembrane protein 1), also known as gl (gray-lethal) or HSPC019, is a 338 amino acid single-pass type I membrane protein that is expressed primarily in osteoclasts and melanocytes as well as brain, kidney and spleen. Bone autosomal recessive osteopetrosis (ARO) is the most severe form of hereditary bone disease whose cellular basis is in the osteoclast and is characterized by abnormally dense bone, due to defective resorption of immature bone. ARO is suggested to be caused by mutations in the OSTM1 gene. The disorder occurs in two forms: a severe autosomal recessive form occurring in utero, infancy, or childhood, and a benign autosomal dominant form occurring in adolescence or adulthood. Defects in the OSTM1 gene are also the cause of the spontaneous gl mutant, which is responsible for a coat color defect in mice.
抗原信息
免疫原
KLH conjugated synthetic peptide: human OSTM1
抗原种属
Human
基因名称
OSTM1
基因ID
28962
蛋白名称
Osteopetrosis-associated transmembrane protein 1
Uniprot ID
Q86WC4
功能
Required for osteoclast and melanocyte maturation and function (By similarity).
化学信息
分子量Theoretical: 33 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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