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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-NPC1 Polyclonal Antibody

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货号 TMAB-09583

Anti-NPC1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NPC1。Anti-NPC1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-NPC1 Polyclonal Antibody

Anti-NPC1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-09583

Anti-NPC1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NPC1。Anti-NPC1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-NPC1 Polyclonal Antibody is a Rabbit antibody targeting NPC1. Anti-NPC1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Pig,GuineaPig)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Late endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments.[provided by RefSeq, Aug 2009].
抗原信息
免疫原
KLH conjugated synthetic peptide: mo NPC1/Niemann Pick C1
基因名称
NPC1
基因ID
4864
蛋白名称
NPC intracellular cholesterol transporter 1
功能
Involved in the intracellular trafficking of cholesterol. May play a role in vesicular trafficking in glia, a process that may be crucial for maintaining the structural and functional integrity of nerve terminals.
化学信息
分子量Theoretical: 138 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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