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IL-4 Protein, Human, Recombinant V2

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产品编号 TMPY-01862U

IL-4 Protein, Human, Recombinant V2 is expressed in E. coli. The accession number is P05112.

IL-4 Protein, Human, Recombinant V2

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产品编号 TMPY-01862U

IL-4 Protein, Human, Recombinant V2 is expressed in E. coli. The accession number is P05112.

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产品信息

生物活性	Immobilized Human AXL-His at 10 μg/ml (100 μl/well) can bind Human GAS6-His.: Biotinylated by NHS-biotin prior to testing The ED50 of Recombinant Human GAS6-His* is 0.04466 μg/ml. (Regularly tested)
产品描述	IL-4 Protein, Human, Recombinant V2 is expressed in E. coli. The accession number is P05112.
种属	Human
表达系统	E. coli
蛋白编号	P05112
别名	白介素,Interleukin-4,interleukin 4,IL-4,BSF-1,BSF1,BCGF-1,BCGF1
蛋白构建	His25-Ser153
蛋白纯度	> 95% as determined by SDS-PAGE
分子量	15.1 kDa (Predicted); 13-14 kDa (Reducing conditions)
内毒素	< 0.01 EU/μg of the protein as determined by the LAL method.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 7.2.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal cells. IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergic response.