Name: Ibrexafungerp citrate
Brand: TargetMol
SKU: T70029
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 mg

待询

50 mg

待询

100 mg

待询

生物活性

产品描述	Ibrexafungerp citrate is a triterpenoid antifungal agent that inhibits the synthesis of 1,3-β-D-glucan in fungal cell walls, and although its functional outcome is similar to echinocandins, it binds to a distinct site on the glucan synthase enzyme, resulting in limited cross-resistance. Ibrexafungerp citrate exhibit concentration-dependent fungicidal activity against Candida species and retaining strong in vitro efficacy against the majority of fluconazole-resistant strains, supporting its use in antifungal resistance and drug development research.
体外活性	在真菌敏感性测定中，Ibrexafungerp citrate 作为 β-1,3-葡聚糖合成酶抑制剂，破坏细胞壁完整性。对包括多重耐药耳念珠菌在内的多种念珠菌属表现出 0.5 μg/mL 的最小抑菌浓度 (MIC50)，产生广谱杀真菌活性 [1]。
别名	枸橼酸艾瑞芬净, SCY-078 citrate, SCY078 citrate, MK3118 citrate, MK 3118 citrate

化学信息

分子量	922.16
分子式	C₅₀H₇₅N₅O₁₁
CAS No.	1965291-08-0
Smiles	C(CC(O)=O)(CC(O)=O)(C(O)=O)O.C[C@@]12[C@]3([C@@](C=4[C@@]([C@]5(C)[C@@](C)(CC4)[C@H](C(O)=O)[C@]([C@@H](C(C)C)C)(C)CC5)(CC3)[H])(C[C@H]([C@@H]1OC[C@](C(C)(C)C)(C)N)N6C(=NC=N6)C=7C=CN=CC7)COC2)[H]

储存&溶解度

存储

In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 80 mg/mL (86.75 mM), Sonication is recommended.

溶液配制表

DMSO

Ibrexafungerp citrate