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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-IKBKB Monoclonal Antibody (6V122)

Synonyms: IKBKB
货号 TMAT-0524 一键复制产品信息
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Anti-IKBKB Monoclonal Antibody (6V122) 是一种 Mouse 抗体，靶向 IKBKB。Anti-IKBKB Monoclonal Antibody (6V122) 可用于 IHC。

Anti-IKBKB Monoclonal Antibody (6V122)

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货号 TMAT-0524

别名 IKBKB

Anti-IKBKB Monoclonal Antibody (6V122) 是一种 Mouse 抗体，靶向 IKBKB。Anti-IKBKB Monoclonal Antibody (6V122) 可用于 IHC。

Anti-IKBKB Monoclonal Antibody (6V122)
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产品介绍

生物活性
产品描述
Anti-IKBKB Monoclonal Antibody (6V122) is a Mouse antibody targeting IKBKB. Anti-IKBKB Monoclonal Antibody (6V122) can be used in IHC.
别名
IKBKB
Ig Type
IgG1
克隆号
6V122
反应种属
Human
应用IHC
推荐剂量
IHC: 1/200-1/1000
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液Ascitic fluid containing 0.03% sodium azide
浓度1 mg/ml
研究背景IKBKB(Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, also called IKK2/IKKB), is a member of the IKK complex which is composed of IKK-alpha, IKK-beta, IKK-gamma and IKAP. Phosphorylation of I-Kappa-B on a serine residue by the IKK complex frees NF-kB from I-Kappa-B and marks it for degradation via ubiquination. IKK-beta has been shown to activate NF-kB and phosphorylate IKB-alpha and beta. Phosphorylation of 2 sites at the activation loop of IKK-beta is essential for activation of IKK by TNF and IL1. Once activated, IKK-beta autophosphorylates which in turn decreases IKK activity and prevents prolonged activation of the inflammatory response. Additionally, IKK-beta activity can also be regulated by MEKK-1.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of IKBKB expressed in E. Coli.
抗原种属
Human
基因名称
IKBKB
基因ID
3551
蛋白名称
Inhibitor of nuclear factor kappa-B kinase subunit beta
Uniprot ID
O14920
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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  • 配液 计算器
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