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Anti-NQO2 Antibody (1E974)
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产品编号 TMAC-02886
别名 Ribosyldihydronicotinamide dehydrogenase [quinone], Quinone reductase 2, QR2, NRH:quinone oxidoreductase 2, NRH dehydrogenase [quinone] 2, NQO 2, NMOR2, EC 1.10.5.1
Anti-NQO2 Antibody (1E974) 是一种 Rabbit 抗体，靶向 NQO2。Anti-NQO2 Antibody (1E974) 可用于 WB。
Anti-NQO2 Antibody (1E974)
Anti-NQO2 Antibody (1E974)
还可以产品编号 TMAC-02886 别名 Ribosyldihydronicotinamide dehydrogenase [quinone], Quinone reductase 2, QR2, NRH:quinone oxidoreductase 2, NRH dehydrogenase [quinone] 2, NQO 2, NMOR2, EC 1.10.5.1
Anti-NQO2 Antibody (1E974) 是一种 Rabbit 抗体，靶向 NQO2。Anti-NQO2 Antibody (1E974) 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,485 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
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| 产品描述 | Anti-NQO2 Antibody (1E974) is a Rabbit antibody targeting NQO2. Anti-NQO2 Antibody (1E974) can be used in WB. |
| 别名 | Ribosyldihydronicotinamide dehydrogenase [quinone], Quinone reductase 2, QR2, NRH:quinone oxidoreductase 2, NRH dehydrogenase [quinone] 2, NQO 2, NMOR2, EC 1.10.5.1 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of NQO2 on Hela cells lysates using anti-NQO2 antibody at 1/1,000 dilution. |
| 应用 | |
| 推荐剂量 | WB: 1:1000-2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | NAD(P)H:quinone oxidoreductase 1 (NQO1) and NRH:quinone oxidoreductase (NQO2) are flavoproteins that catalyze the metabolic detoxification of quinones and their derivatives to hydroquinones. This detoxification process protects cells against quinone-induced oxidative stress, cytotoxicity and mutagenicity. NQO2 is a 231 amino acid protein and is 43 amino acids shorter than NQO1 at its C-terminus. NQO2 is an isozyme of NQO1 and transfers two electrons to a quinone, resulting in the formation of a hydroquinone product . The NQO2 gene is ubiquitously expressed and induced in response to TCDD. NQO2 has a higher level of expression in mouse liver and testis than NQO1, which is highly expressed in the heart. NQO2 has a different cofactor requirement than NQO1 and uses dihydronicotinamide riboside (NRH) rather than NAD(P)H as an electron donor. Unlike NQO1, NQO2 is resistant to typical inhibitors of NQO1 such as dicoumarol, Cibacron blue and phenindonee, but is inhibited by quercetin and benzo(a)pyrene. NQO2 contains a specific metal binding site, which is absent in NQO1 and several cis-elements including SP1 binding sites, CCAAT box, XRE and ARE, which are located at the NQO2 gene promoter. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 26 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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