VEGF165 Protein, Human, Recombinant (Verified Cell Activity) is expressed in Baculovirus Insect Cells. The accession number is NP_001165097.

Baculovirus Insect Cells

血管内皮生长因子,VEGFA,VEGF-165,VEGF165,Vascular Endothelial Growth Factor Isoform 165

Ala27-Arg191, Disulfide-linked homodimer

Reconstitute at 100‑500 μg/mL in sterile 4 mM HCl containing 0.1% human or bovine serum albumin.

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator in vasculogenesis and angiogenesis both physiologically and pathologically. VEGF-A has 8 differently spliced isoforms, of which VEGF165 is the most abundant one. VEGF165 is a disulfide-linked homodimer consisting of two glycosylated 165 amino acid polypeptide chains. VEGF stimulates the cellular response through binding to tyrosine kinase receptors VEGFR1 and VEGFR2 on the cell surface. It is widely accepted that VEGFR2 mediate almost all of the known cellular responses to VEGF while the function of VEGFR1 is less defined and is thought to modulate the VEGFR2 signaling.