Spectinomycin dihydrochloride

Name: Spectinomycin dihydrochloride
Brand: TargetMol
SKU: T0788
Price: 183 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 99.9%

货号 T0788Cas号 21736-83-4

别名 盐酸奇霉素, 淋必治, Spectinomycin 2HCl, Actinospectacin

Spectinomycin dihydrochloride (Actinospectacin) 是一种能与细菌核糖体的30S 亚基结合，干扰蛋白质合成的抗生素。

Spectinomycin dihydrochloride

一键复制产品信息

很棒

纯度: 99.9%

货号 T0788 别名 盐酸奇霉素, 淋必治, Spectinomycin 2HCl, ActinospectacinCas号 21736-83-4

Spectinomycin dihydrochloride (Actinospectacin) 是一种能与细菌核糖体的30S 亚基结合，干扰蛋白质合成的抗生素。

规格	价格	库存
100 mg	¥ 183	现货
500 mg	¥ 395	现货
1 g	¥ 494	现货
5 g	¥ 788	现货
10 g	¥ 1,150	现货

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纯度: 99.9%

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产品介绍

Spectinomycin dihydrochloride AI Summary

Spectinomycin dihydrochloride exhibits multiple bioactivities according to provided data. It inhibits Human Apurinic/apyrimidinic Endonuclease 1 (APE1) with a potency of 17782.8 nM. In assays related to GLP1 secretion from STC-1 and NCI-H716 cells, it has an IC50 of 40000.0 nM. Additionally, it blocks the entry of the Ebola Virus, showing an AC50 of 2.239 µM in one screening assay and AC50 values of 2238.7 nM and 1778.3 nM in different assays. However, Spectinomycin dihydrochloride demonstrates low activity in inhibiting cell viability in Vero E6 cells infected with SARS-CoV-2, with an inhibition index of 0.1494, indicating limited efficacy compared to the arbidol control..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Spectinomycin dihydrochloride (Actinospectacin) is an antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.
别名	盐酸奇霉素, 淋必治, Spectinomycin 2HCl, Actinospectacin

化学信息

分子量	405.271
分子式	C₁₄H₂₆Cl₂N₂O₇
CAS No.	21736-83-4
Smiles	Cl.Cl.CN[C@@H]1[C@H](O)[C@H](NC)[C@H]2O[C@]3(O)[C@@H](O[C@H](C)CC3=O)O[C@@H]2[C@H]1O
密度	1.43g/cm3
颜色	White
物理性状	Solid

储存&溶解度

存储

store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

H2O: 74 mg/mL (182.59 mM), Sonication is recommended.

DMSO: 242.5 mg/mL (598.37 mM), Sonication is recommended.

溶液配制表

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4675 mL	12.3374 mL	24.6748 mL	123.3742 mL
5 mM	0.4935 mL	2.4675 mL	4.9350 mL	24.6748 mL
10 mM	0.2467 mL	1.2337 mL	2.4675 mL	12.3374 mL
20 mM	0.1234 mL	0.6169 mL	1.2337 mL	6.1687 mL
50 mM	0.0493 mL	0.2467 mL	0.4935 mL	2.4675 mL
100 mM	0.0247 mL	0.1234 mL	0.2467 mL	1.2337 mL