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Anti-GRP78/Bip Antibody (4S162)

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货号 TMAB-06799

Anti-GRP78/Bip Antibody (4S162) 是一种 Mouse 抗体，靶向 GRP78/Bip。Anti-GRP78/Bip Antibody (4S162) 可用于 WB,ICC/IF。

Anti-GRP78/Bip Antibody (4S162)

Anti-GRP78/Bip Antibody (4S162)

一键复制产品信息
Rating icon 还可以
货号 TMAB-06799

Anti-GRP78/Bip Antibody (4S162) 是一种 Mouse 抗体，靶向 GRP78/Bip。Anti-GRP78/Bip Antibody (4S162) 可用于 WB,ICC/IF。

规格价格库存数量
200 μg
¥ 5,595
5日内发货
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-GRP78/Bip Antibody (4S162) is a Mouse antibody targeting GRP78/Bip. Anti-GRP78/Bip Antibody (4S162) can be used in WB,ICC/IF.
Ig Type
IgG
克隆号
4S162
反应种属
Human (predicted:Rat)
应用WBICC/IF
推荐剂量
WB: 1:500-1000; ICC/IF: 1:100-500
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Endoplasmic reticulum lumen. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The 78 kDa glucose regulated protein/BiP (GRP78) belongs to the family of ~70 kDa heat shock proteins (HSP 70). GRP78 is a resident protein of the endoplasmic reticulum (ER) and may associate transiently with a variety of newly synthesized secretory and membrane proteins or permanently with mutant or defective proteins that are incorrectly folded, thus preventing their export from the ER lumen. GRP78 is a highly conserved protein that is essential for cell viability. The highly conserved sequence Lys-Asp-Glu-Leu (KDEL) is present at the C terminus of GRP78 and other resident ER proteins including glucose regulated protein 94 (GRP 94) and protein disulfide isomerase (PDI). The presence of carboxy terminal KDEL appears to be necessary for retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.
抗原信息
免疫原
KLH conjugated synthetic peptide: human GRP78/Bip
抗原种属
Human
基因名称
HSPA5
基因ID
3309
蛋白名称
Endoplasmic reticulum chaperone BiP
Uniprot ID
P11021
功能
Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.
化学信息
分子量Theoretical: 78 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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