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Anti-NT-proBNP/NPPB Antibody (2S162)

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货号 TMAB-09661

Anti-NT-proBNP/NPPB Antibody (2S162) 是一种 Mouse 抗体，靶向 NT-proBNP/NPPB。Anti-NT-proBNP/NPPB Antibody (2S162) 可用于 WB。

Anti-NT-proBNP/NPPB Antibody (2S162)

Anti-NT-proBNP/NPPB Antibody (2S162)

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Rating icon 还可以
货号 TMAB-09661

Anti-NT-proBNP/NPPB Antibody (2S162) 是一种 Mouse 抗体，靶向 NT-proBNP/NPPB。Anti-NT-proBNP/NPPB Antibody (2S162) 可用于 WB。

规格价格库存数量
200 μg
¥ 5,585
5日内发货
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-NT-proBNP/NPPB Antibody (2S162) is a Mouse antibody targeting NT-proBNP/NPPB. Anti-NT-proBNP/NPPB Antibody (2S162) can be used in WB.
Ig Type
IgG
克隆号
2S162
反应种属
Human
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Secreted.
组织特异性Brain and also in atria, but at much lower levels than ANP.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Brain natriuretic peptide (BNP), also known as B-type natriuretic peptide, is a hormone secreted by cardiomyocytes in the heart ventricles in response to stretching caused by increased ventricular blood volume. The 32-amino acid polypeptide BNP is secreted attached to a 76–amino acid N-terminal fragment in the prohormone called NT-proBNP (BNPT), which is biologically inactive. Once released, BNP binds to and activates the atrial natriuretic factor receptor NPRA, and to a lesser extent NPRB, in a fashion similar to atrial natriuretic peptide (ANP) but with 10-fold lower affinity. The biological half-life of BNP, however, is twice as long as that of ANP, and that of NT-proBNP is even longer, making these peptides better targets than ANP for diagnostic blood testing.
抗原信息
免疫原
Recombinant Protein: human NT-proBNP protein
抗原种属
Human
基因名称
NPPB
基因ID
4879
蛋白名称
Natriuretic peptides B
Uniprot ID
P16860
功能
Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
化学信息
分子量Theoretical: 8.5/15 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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