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Anti-ADCY3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ADCY3。Anti-ADCY3 Polyclonal Antibody 可用于 WB。
Anti-ADCY3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ADCY3。Anti-ADCY3 Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,160 | 5日内发货 | |
100 μL | ¥ 1,960 | 5日内发货 | |
200 μL | ¥ 2,785 | 5日内发货 |
产品描述 | Anti-ADCY3 Polyclonal Antibody is a Rabbit antibody targeting ADCY3. Anti-ADCY3 Polyclonal Antibody can be used in WB. |
疾病造模方案 | |
别名 | KIAA0511, ATP pyrophosphate-lyase 3, Adenylyl cyclase 3 (AC3), Adenylate cyclase, olfactive type, Adenylate cyclase type III (AC-III), Adenylate cyclase type 3, ADCY3 |
Ig Type | IgG |
交叉反应 | Mouse (predicted:Human,Rat,Pig,Cow,Horse,Sheep) |
验证活性 | Sample: Spleen (mouse) Lysate at 40 μg Primary: Anti-ADCY3 (TMAB-00059) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 126 kDa Observed band size: 126 kDa |
应用 | |
推荐剂量 | WB: 1:500-2000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
亚细胞定位 | Membrane; Multi-pass membrane protein. |
组织特异性 | Expressed in brain, heart, kidney, liver, lung, pancreas, placenta, and skeletal muscle. |
构建方式 | Polyclonal Antibody |
纯化方式 | Protein A purified |
性状 | Liquid |
缓冲液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
浓度 | 1 mg/mL |
研究背景 | The cAMP synthesizing enzymes are found in two forms: cytosolic (soluble) and membrane-bound (particulate). Stimulation of adenylate cyclases produce cAMP form ATP in response to the activation of GPCRs by various hormones, neurotransmitters and other regulatory molecules. cAMP, in subsequent steps down the signal transduction pathway, can stimulate cAMP-dependent protein kinase A (cPKA), and several other target molecules. Activation of cPKA can phosphorylate a broad range of substrates that regulate various metabolic pathways, gene expression, and affect memory functions etc. The stimulation of adenylate cyclases starts with interactions with GPCRs mediated signals initiated by Gs and Gi heterotrimeric G-proteins. |
免疫原 | KLH conjugated synthetic peptide: human ADCY3 |
抗原种属 | Human |
基因名称 | ADCY3 |
基因ID | |
蛋白名称 | Adenylate cyclase type 3 |
Uniprot ID | |
研究领域 | Integration of energy metabolism,Integration of energy,Cancer,GPCR |
功能 | Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration. |
分子量 | Theoretical: 126 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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