生物活性

产品描述	TL1A/TNFSF15 Protein, Cynomolgus/Rhesus macaque, Recombinant (Fc) is expressed in HEK293 Cells. The accession number is A0A2K5UA22(Cynomolgus)/F6S8F9(Rhesus macaque).
生物活性	Immobilized Cynomolgus/Rhesus macaque TNFSF15, hFc Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-TNFSF15 Antibody, hFc Tag with the EC50 of 14.6 ng/ml determined by ELISA.
研究背景	TNF superfamily member 15 (TNFSF15), a cytokine largely produced by vascular endothelial cells and a specific inhibitor of the proliferation of these same cells, can inhibit VEGF-induced vascular permeability in vitro and in vivo, and that death receptor 3 (DR3), a cell surface receptor of TNFSF15, mediates TNFSF15-induced dephosphorylation of VEGFR2.
种属	Cynomolgus/Rhesus macaque
表达系统	HEK293 Cells
标签	N-monomeric Fc
蛋白编号	A0A2K5UA22 (Cynomolgus)/F6S8F9 (Rhesus macaque)
蛋白构建	Leu72-Leu251
蛋白纯度	> 95% as determined by Bis-Tris PAGE; > 90% as determined by HPLC
缓冲液	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
内毒素	< 1 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	44.82 kDa (Predicted); 50-60 kDa (Reducing condition, due to glycosylation)

储存&溶解度

运输方式

In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.

存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

TL1A/TNFSF15 Protein, Cynomolgus/Rhesus macaque, Recombinant (Fc)

TL1A/TNFSF15 Protein, Cynomolgus/Rhesus macaque, Recombinant (Fc)

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