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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Phospho-Ephrin B (Ser300) Polyclonal Antibody

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货号 TMAB-10658

Anti-Phospho-Ephrin B (Ser300) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-Ephrin B (Ser300)。Anti-Phospho-Ephrin B (Ser300) Polyclonal Antibody 可用于 WB。

Anti-Phospho-Ephrin B (Ser300) Polyclonal Antibody

Anti-Phospho-Ephrin B (Ser300) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-10658

Anti-Phospho-Ephrin B (Ser300) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-Ephrin B (Ser300)。Anti-Phospho-Ephrin B (Ser300) Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

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产品描述
Anti-Phospho-Ephrin B (Ser300) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Ephrin B (Ser300). Anti-Phospho-Ephrin B (Ser300) Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein.
组织特异性Highly expressed in brain; expressed in embryonic floor plate, roof plate and hindbrain segments.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Ephrin B proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development. Ephrin B molecules expressed at the membrane surface bind to the Ephrin B family receptors on target cells during cell to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing Ephrin B on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of Ephrin B is thought to be a critical component of this reverse signaling event. Recent work demonstrated that Tyr331 of Ephrin B was phosphorylated in HEK293 cells after stimulation by the soluble Ephrin B2 receptor tyrosine kinase.
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human Ephrin B around the phosphorylation site of Ser300
抗原种属
Human
基因名称
EFNB1
基因ID
1947
蛋白名称
Ephrin-B1
Uniprot ID
P98172
功能
Binds to the receptor tyrosine kinases EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons.
Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to the receptor tyrosine kinases EPHB3 (preferred), EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons.
化学信息
分子量Theoretical: 38 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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