购物车
- 全部删除
- 您的购物车当前为空
FT011 是抗纤维化剂,能够抑制胶原蛋白 I 和 III 的 mRNA 表达,减少胶原蛋白合成。
为众多的药物研发团队赋能,
让新药发现更简单!
FT011 是抗纤维化剂,能够抑制胶原蛋白 I 和 III 的 mRNA 表达,减少胶原蛋白合成。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 185 | 现货 | |
5 mg | ¥ 398 | 现货 | |
10 mg | ¥ 663 | 现货 | |
25 mg | ¥ 1,270 | 现货 | |
50 mg | ¥ 2,320 | 现货 | |
100 mg | ¥ 3,730 | 现货 | |
200 mg | ¥ 4,720 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 455 | 现货 |
产品描述 | FT011, a direct anti-fibrotic agent,attenuates cardiac remodelling and dysfunction in experimental diabetic cardiomyopathy. |
体内活性 | A direct anti-fibrotic agent, FT011, attenuates cardiac remodelling and dysfunction in experimental diabetic cardiomyopathy[1]. |
动物实验 | Homozygous Ren-2 rats were randomized to receive streptozotocin or vehicle then further randomized to FT011 (200 mg/kg/day) or vehicle treatment for 6 weeks. Prior to tissue collection, cardiac function was assessed via echocardiography and cardiac catheterization. Total collagen deposition and cardiomyocyte hypertrophy were assessed by picrosirius red and haematoxylin and eosin staining, respectively. Macrophage interstitial infiltration and type I and III collagen were quantitated by immunostaining[1]. |
分子量 | 351.35 |
分子式 | C20H17NO5 |
CAS No. | 1001288-58-9 |
Smiles | COc1cc(\C=C\C(=O)Nc2ccccc2C(O)=O)ccc1OCC#C |
密度 | 1.307 g/cm3 (Predicted) |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 29 mg/mL (82.54 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
溶液配制表 | |||||||||||||||||||||||||||||||
DMSO
|
以上为“体内实验配液计算器”的使用方法举例,并不是具体某个化合物的推荐配制方式,请根据您的实验动物和给药方式选择适当的溶解方案。
评论内容