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Anti-Glutamine synthetase Polyclonal Antibody

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货号 TMAB-06558

Anti-Glutamine synthetase Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Glutamine synthetase。Anti-Glutamine synthetase Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Glutamine synthetase Polyclonal Antibody

Anti-Glutamine synthetase Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-06558

Anti-Glutamine synthetase Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Glutamine synthetase。Anti-Glutamine synthetase Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-Glutamine synthetase Polyclonal Antibody is a Rabbit antibody targeting Glutamine synthetase. Anti-Glutamine synthetase Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Mitochondrion.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Glutamine Synthetase catalyzes the conversion of ammonia and glutamate to glutamine. It is found in astrocytes as an octamer of identical 42 kDa subunits. The function of Glutamine Synthetase is the detoxification of brain ammonia. It also has an important role in the metabolic regulation of neurotransmitter glutamate. Because of the multiple functions and importance of Glutamine Synthetase in cellular metabolism, both catalytic activities and synthesis are highly regulated. The activity of Glutamine Synthetase is controlled by adenylylation. Its activity is decreased in the cerebral cortex of brains affected by Alzheimer's disease, particularly in the vicinity of senile plaques. It is also decreased under conditions of glucose deprivation. The level of expression of Glutamine Synthetase is increased during ischemia in vivo or hypoxia in culture.
抗原信息
免疫原
Recombinant Protein: human Glutamine synthetase protein
抗原种属
Human
基因名称
GLUL
基因ID
蛋白名称
Glutamine synthetase
Uniprot ID
功能
This enzyme has 2 functions: it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner (By similarity). Essential for proliferation of fetal skin fibroblasts.
化学信息
分子量Theoretical: 42 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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