Name: RNF43 Protein, Human, Recombinant (hFc)
Brand: TargetMol
SKU: TMPY-04149
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 428

6-8日内发货

10 μg

¥ 683

6-8日内发货

20 μg

¥ 1,130

5日内发货

50 μg

¥ 2,270

5日内发货

100 μg

¥ 4,430

5日内发货

生物活性

产品描述	RNF43 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.8 kDa and the accession number is Q68DV7-1.
生物活性	Immobilized Human R spondin 1, His Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Human RNF34, hFc Tag with the EC50 of 0.4 μg/ml determined by ELISA.
研究背景	RNF43 (E3 ubiquitin-protein ligase RNF43 or RING-type E3 ubiquitin transferase RNF43) functions as a tumor suppressor, by exerting a predominant negative feedback mechanism in the Wnt/β-catenin signaling pathway. RNF43 inhibits Wnt/beta-catenin signaling by ubiquitinating Frizzled receptor and targeting it to the lysosomal pathway for degradation.
种属	Human
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	Q68DV7-1
蛋白构建	Gly24-Tyr197
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	URCC, RNF43, RNF124, ring finger protein 43
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	45.8 kDa (Predicted); 55-60 kDa (Due to glycosylation)

储存&溶解度

运输方式	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
存储

RNF43 Protein, Human, Recombinant (hFc)