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Anti-PRTFDC1 Antibody (6G114)
还可以产品编号 TMAY-02682
Anti-PRTFDC1 Antibody (6G114) 是一种 Mouse 抗体，靶向 PRTFDC1。Anti-PRTFDC1 Antibody (6G114) 可用于 WB,ELISA。
Anti-PRTFDC1 Antibody (6G114)
Anti-PRTFDC1 Antibody (6G114)
还可以产品编号 TMAY-02682
Anti-PRTFDC1 Antibody (6G114) 是一种 Mouse 抗体，靶向 PRTFDC1。Anti-PRTFDC1 Antibody (6G114) 可用于 WB,ELISA。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-PRTFDC1 Antibody (6G114) is a Mouse antibody targeting PRTFDC1. Anti-PRTFDC1 Antibody (6G114) can be used in WB,ELISA. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 6G114 |
| 交叉反应 | Human |
| 验证活性 | Anti-PRTFDC1 mouse monoclonal antibody at 1:500 dilution. -Lane A: 293T Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Mouse IgG H&L (Dylight800) at 1/15000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:28 kDa. -Observed band size:28 kDa |
| 应用 | WB,ELISA |
| 推荐剂量 | WB: 1:500-1:1000; ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human PRTFDC1 (rh PRTFDC1; TMPY-03332; Q9NRG1-1; Met1-Val225). The IgG fraction of the cell culture supernatant was purified by Protein A affinity. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | PRTFDC1 is a member of the purine/pyrimidine phosphoribosyltransferase family. It can bind GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). The epigenetic silencing of PRTFDC1 by hypermethylation of the CpG island leads to a loss of PRTFDC1 function, which might be involved in squamous cell oral carcinogenesis. PRTFDC1 is a genetic modifier of HPRT-deficiency in the mouse and has important implications for unraveling the molecular etiology of lesch-Nyhan disease(LND). LND is a severe X-linked neurological disorder caused by a deficiency of hypoxanthine phosphoribosyltransferase. PRTFDC1 has a low, barely measurable phosphoribosyltransferase activity (in vitro). |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human PRTFDC1 protein (TMPY-03332) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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