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Anti-IL-36 alpha/IL-1F6 Antibody (4S962)
还可以产品编号 TMAY-01022
别名 白细胞介素, interleukin 36, α, interleukin 36, alpha, IL36A, IL36 α/IL-1F6, IL-1F6, IL1F6, IL1E, IL1(ε), IL1(EPSILON), FIL1E, FIL1(ε), FIL1(EPSILON), FIL1, FIL, 1E
Anti-IL-36 alpha/IL-1F6 Antibody (4S962) 是一种 Mouse 抗体，靶向 IL-36 alpha/IL-1F6。Anti-IL-36 alpha/IL-1F6 Antibody (4S962) 可用于 ELISA。
Anti-IL-36 alpha/IL-1F6 Antibody (4S962)
Anti-IL-36 alpha/IL-1F6 Antibody (4S962)
还可以产品编号 TMAY-01022 别名 白细胞介素, interleukin 36, α, interleukin 36, alpha, IL36A, IL36 α/IL-1F6, IL-1F6, IL1F6, IL1E, IL1(ε), IL1(EPSILON), FIL1E, FIL1(ε), FIL1(EPSILON), FIL1, FIL, 1E
Anti-IL-36 alpha/IL-1F6 Antibody (4S962) 是一种 Mouse 抗体，靶向 IL-36 alpha/IL-1F6。Anti-IL-36 alpha/IL-1F6 Antibody (4S962) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 1,684 | 5日内发货 |
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| 产品描述 | Anti-IL-36 alpha/IL-1F6 Antibody (4S962) is a Mouse antibody targeting IL-36 alpha/IL-1F6. Anti-IL-36 alpha/IL-1F6 Antibody (4S962) can be used in ELISA. |
| 别名 | 白细胞介素, interleukin 36, α, interleukin 36, alpha, IL36A, IL36 α/IL-1F6, IL-1F6, IL1F6, IL1E, IL1(ε), IL1(EPSILON), FIL1E, FIL1(ε), FIL1(EPSILON), FIL1, FIL, 1E |
| Ig Type | Monoclonal Mouse IgG2b |
| 克隆号 | 4S962 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL1F6 / IL36A (rh IL1F6 / IL36A; Q9UHA7Met 1-Phe 158). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Interleukin-1 family member 6 (IL-1F6), also known as interleukin 36, alpha (IL36A), is a pro-inflammatory cytokine that plays an important role in innate and adaptive immunity. IL-1F6 activates MAPK and NF-kB pathways and is produced by many different cells. This cytokine is a family member of interleukin-1 (IL-1) and plays an important role in the pathophysiology of several diseases. It has been reported that IL-1F6 and IL-1F8, in addition to IL-1F9, activate the pathway leading to NF-kappaB in an IL-1Rrp2-dependent manner in Jurkat cells as well as in multiple other human and mouse cell lines. Activation of the pathway leading to NF-kappaB by IL-1F6 and IL-1F8 follows a similar time course to activation by IL-1beta, suggesting that signaling by the novel family members occurs through a direct mechanism. In a mammary epithelial cell line, NCI/ADR-RES, which naturally expresses IL-1Rrp2, all three cytokines signal without further receptor transfection. IL-1Rrp2 antibodies block activation of the pathway leading to NF-kappaB by IL-1F6, IL-1F8, and IL-1F9 in both Jurkat and NCI/ADR-RES cells. Thus IL-1F6, IL-1F8, and IL-1F9 signal through IL-1Rrp2 and IL-1RAcP. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human IL1F6 / IL36A protein |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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