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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PNPLA6/NTE Polyclonal Antibody

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货号 TMAB-11603

Anti-PNPLA6/NTE Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PNPLA6/NTE。Anti-PNPLA6/NTE Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-PNPLA6/NTE Polyclonal Antibody

Anti-PNPLA6/NTE Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-11603

Anti-PNPLA6/NTE Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PNPLA6/NTE。Anti-PNPLA6/NTE Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

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产品描述
Anti-PNPLA6/NTE Polyclonal Antibody is a Rabbit antibody targeting PNPLA6/NTE. Anti-PNPLA6/NTE Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Chicken,Dog,Pig,Cow,Horse)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum membrane; Single-pass ype I membrane protein; Cytoplasmic side. Note=Anchored to the cytoplasmic face of the endoplasmic reticulum by its amino-terminal transmembrane segment.
组织特异性Expressed in brain, placenta, kidney, neuron and skeletal muscle.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Its specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy. Tissue specificity;Expressed in brain, placenta, kidney, neuron and skeletal muscle. Involvement in diseaseDefects in PNPLA6 are the cause of spastic paraplegia autosomal recessive type 39 (SPG39) ; also known as NTE-related motor neuron disorder (NTEMND). Spastic paraplegia is a neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. Rate of progression and the severity of symptoms are quite variable. Initial symptoms may include difficulty with balance, weakness and stiffness in the legs, muscle spasms, and dragging the toes when walking. In some forms of the disorder, bladder symptoms (such as incontinence) may appear, or the weakness and stiffness may spread to other parts of the body. SPG39 is associated with a motor axonopathy affecting upper and lower limbs and resulting in progressive wasting of distal upper and lower extremity muscles.
抗原信息
免疫原
KLH conjugated synthetic peptide: human PNPLA6
抗原种属
Human
基因名称
PNPLA6
基因ID
10908
蛋白名称
Patatin-like phospholipase domain-containing protein 6
Uniprot ID
Q8IY17
功能
Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 organophosphorus (OP) compounds leads to distal axonopathy.
化学信息
分子量Theoretical: 150 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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