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Anti-Carboxypeptidase E Antibody (6X802)
还可以产品编号 TMAY-00212
Anti-Carboxypeptidase E Antibody (6X802) 是一种 Rabbit 抗体，靶向 Carboxypeptidase E。Anti-Carboxypeptidase E Antibody (6X802) 可用于 ELISA。
Anti-Carboxypeptidase E Antibody (6X802)
Anti-Carboxypeptidase E Antibody (6X802)
还可以产品编号 TMAY-00212
Anti-Carboxypeptidase E Antibody (6X802) 是一种 Rabbit 抗体，靶向 Carboxypeptidase E。Anti-Carboxypeptidase E Antibody (6X802) 可用于 ELISA。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Carboxypeptidase E Antibody (6X802) is a Rabbit antibody targeting Carboxypeptidase E. Anti-Carboxypeptidase E Antibody (6X802) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 6X802 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CPE (rhCPE; TMPY-01141; NP_001864.1; Met 1-Ser 453). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Carboxypeptidase E (CPE), also known as Carboxypeptidase H, is a peripheral membrane protein and a zinc metallocarboxypeptidase, and the conversion of proCPE into CPE occurs primarily in secretory vesicles. The active form of CPE cleaves C-terminal amino acid residues of the peptide, and is thus involved in the biosynthesis of peptide hormones and neurotransmitters including insulin, enkephalin, etc. The enzymatic activity is enhanced by millimolar concentrations of Co2+. It has also been proposed that membrane-associated carboxypeptidase E acts as a sorting receptor for targeting regulated secretory proteins which are mostly prohormones and neuropeptides in the trans-Golgi network of the pituitary and in secretory granules into the secretory pathway.Its interaction with glycosphingolipid-cholesterol rafts at the TGN facilitates the targeting. Mutations in this gene are implicated in type II diabetes due to impaired glucose clearance and insulin resistance. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human CPE protein (TMPY-01141) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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