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Anti-Carboxypeptidase E Antibody (6X802)

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Anti-Carboxypeptidase E Antibody (6X802)
产品编号 TMAY-00212
别名 carboxypeptidase E

Anti-Carboxypeptidase E Antibody (6X802) 是一种 Rabbit 抗体，靶向 Carboxypeptidase E。Anti-Carboxypeptidase E Antibody (6X802) 可用于 ELISA。

Anti-Carboxypeptidase E Antibody (6X802)
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Anti-Carboxypeptidase E Antibody (6X802)

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Anti-Carboxypeptidase E Antibody (6X802)
产品编号 TMAY-00212 别名 carboxypeptidase E

Anti-Carboxypeptidase E Antibody (6X802) 是一种 Rabbit 抗体，靶向 Carboxypeptidase E。Anti-Carboxypeptidase E Antibody (6X802) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,294
5日内发货
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产品介绍

生物活性
产品描述
Anti-Carboxypeptidase E Antibody (6X802) is a Rabbit antibody targeting Carboxypeptidase E. Anti-Carboxypeptidase E Antibody (6X802) can be used in ELISA.
别名carboxypeptidase E
Ig Type
Rabbit IgG
克隆号
6X802
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human CPE (rhCPE; TMPY-01141; NP_001864.1; Met 1-Ser 453).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Carboxypeptidase E (CPE), also known as Carboxypeptidase H, is a peripheral membrane protein and a zinc metallocarboxypeptidase, and the conversion of proCPE into CPE occurs primarily in secretory vesicles. The active form of CPE cleaves C-terminal amino acid residues of the peptide, and is thus involved in the biosynthesis of peptide hormones and neurotransmitters including insulin, enkephalin, etc. The enzymatic activity is enhanced by millimolar concentrations of Co2+. It has also been proposed that membrane-associated carboxypeptidase E acts as a sorting receptor for targeting regulated secretory proteins which are mostly prohormones and neuropeptides in the trans-Golgi network of the pituitary and in secretory granules into the secretory pathway.Its interaction with glycosphingolipid-cholesterol rafts at the TGN facilitates the targeting. Mutations in this gene are implicated in type II diabetes due to impaired glucose clearance and insulin resistance.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human CPE protein (TMPY-01141)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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