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IL-13 Protein, Human, Recombinant (His & Avi)
Synonyms: P600, NC30, MGC116789, MGC116788, MGC116786, interleukin 13, IL-13, IL13, BHR1, ALRH货号 TMPK-00617 一键复制产品信息
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Interleukin-13 (IL-13) is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Positively regulates IL31RA expression in macrophages (By similarity).
IL-13 Protein, Human, Recombinant (His & Avi)
一键复制产品信息 很棒SPR兼容缓冲液
货号 TMPK-00617
别名 P600, NC30, MGC116789, MGC116788, MGC116786, interleukin 13, IL-13, IL13, BHR1, ALRH
Interleukin-13 (IL-13) is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Positively regulates IL31RA expression in macrophages (By similarity).
其他形式的 “IL-13 Protein, Human, Recombinant (His & Avi)”:
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 313 | 现货 | |
| 10 μg | ¥ 498 | 3日内发货 | |
| 20 μg | ¥ 793 | 3日内发货 | |
| 50 μg | ¥ 1,580 | 3日内发货 | |
| 100 μg | ¥ 2,660 | 3日内发货 | |
| 200 μg | ¥ 4,790 | 3日内发货 | |
| 500 μg | ¥ 10,600 | 现货 |
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纯度: > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
颜色: 白色
性状: Lyophilized powder
资源下载: COA重组蛋白用户指南
产品介绍
生物活性
化学信息
储存&溶解度
| 产品描述 | Interleukin-13 (IL-13) is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Positively regulates IL31RA expression in macrophages (By similarity). |
| 生物活性 | 1. Immobilized Human IL-13, His Tag at 5μg/ml (100μl/Well). Dose response curve for Human IL-13Ra1, hFc Tag with the EC50 of 4.7μg/ml determined by ELISA.
2. Human IL-13, His Tag immobilized on CM5 Chip can bind Human IL-13Ra1, hFc Tag with an affinity constant of 0.7μM as determined in a SPR assay. |
| 研究背景 | Interleukin-13 (IL-13) is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Positively regulates IL31RA expression in macrophages (By similarity). |
| 种属 | Human |
| 表达系统 | HEK293 Cells |
| 标签 | N-His-Avi |
| 蛋白编号 | AAK53823 |
| 蛋白构建 | Gly21-Asn132 |
| 蛋白纯度 | > 90% as determined by Tris-Bis PAGE |
| 蛋白性状 | Lyophilized powder |
| 缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| 复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 别名 | P600, NC30, MGC116789, MGC116788, MGC116786, interleukin 13, IL-13, IL13, BHR1, ALRH |
| 内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
| 分子量 | 15.3 kDa (predicted). Due to glycosylation, the protein migrates to 15 kDa and 25-45 kDa based on Tris-Bis PAGE result. |
| 运输方式 | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| 存储 | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. 实际储存温度请以COA为准 |
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