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Anti-GALNT13 Polyclonal Antibody

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Anti-GALNT13 Polyclonal Antibody
产品编号 TMAB-00737

Anti-GALNT13 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GALNT13。Anti-GALNT13 Polyclonal Antibody 可用于 WB。

Anti-GALNT13 Polyclonal Antibody

Anti-GALNT13 Polyclonal Antibody

Rating icon 还可以
Anti-GALNT13 Polyclonal Antibody
产品编号 TMAB-00737

Anti-GALNT13 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GALNT13。Anti-GALNT13 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-GALNT13 Polyclonal Antibody is a Rabbit antibody targeting GALNT13. Anti-GALNT13 Polyclonal Antibody can be used in WB.
Ig Type
IgG
交叉反应
Rat (predicted:Human,Mouse,Dog,Pig,Cow,Rabbit,Sheep)
验证活性
Sample: VSC4.1 Cell (Rat) Lysate at 40 μg
Primary: Anti-GALNT13 (TMAB-00737) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 64 kDa
Observed band size: 62 kDa
应用
WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Golgi apparatus membrane; Single pass type II membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景The UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosamine) to serine and threonine residues onto various proteins, thereby initiating mucin-type O-linked glycosylation in the Golgi apparatus. GalNAc-T13 (Polypeptide N-acetylgalactosaminyltransferase 13), also known as UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13, is a 556 amino acid protein that displays much stronger enzymatic activity than GalNAc-1 towards GalNAc transfer to mucin peptides such as Muc5a and Muc7. The N-terminal domain is involved in substrate binding and manganese coordination, while the C-terminal domain is involved in UDP-Gal binding and catalytic reaction. With specific expression in the central nervous system, GalNAc-T13 may be responsible for the synthesis of Tn antigen in neuronal cells, which is a universal carcinoma marker on malignant cells.
抗原信息
免疫原
KLH conjugated synthetic peptide: human GALNT13/GalNAc-T13
抗原种属
Human
基因ID
114805
Uniprot ID
Q8IUC8
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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