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Anti-GALNT13 Polyclonal Antibody

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Anti-GALNT13 Polyclonal Antibody
产品编号 TMAB-00737
别名 UDP N acetyl alpha D galactosamine:polypeptide, UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 13, Protein UDP acetylgalactosaminyltransferase 13, pp GaNTase 13, Polypeptide GalNAc transferase 13, N acetylgalactosaminyltransferase 13, GLT13, GalNAc-T13, GalNAc transferase 13

Anti-GALNT13 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GALNT13。Anti-GALNT13 Polyclonal Antibody 可用于 WB。

Anti-GALNT13 Polyclonal Antibody

Anti-GALNT13 Polyclonal Antibody

Rating icon 还可以
Anti-GALNT13 Polyclonal Antibody
产品编号 TMAB-00737 别名 UDP N acetyl alpha D galactosamine:polypeptide, UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 13, Protein UDP acetylgalactosaminyltransferase 13, pp GaNTase 13, Polypeptide GalNAc transferase 13, N acetylgalactosaminyltransferase 13, GLT13, GalNAc-T13, GalNAc transferase 13

Anti-GALNT13 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GALNT13。Anti-GALNT13 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-GALNT13 Polyclonal Antibody is a Rabbit antibody targeting GALNT13. Anti-GALNT13 Polyclonal Antibody can be used in WB.
疾病造模方案
别名UDP N acetyl alpha D galactosamine:polypeptide, UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 13, Protein UDP acetylgalactosaminyltransferase 13, pp GaNTase 13, Polypeptide GalNAc transferase 13, N acetylgalactosaminyltransferase 13, GLT13, GalNAc-T13, GalNAc transferase 13
Ig Type
IgG
交叉反应
Rat (predicted:Human,Mouse,Dog,Pig,Cow,Rabbit,Sheep)
验证活性
Sample: VSC4.1 Cell (Rat) Lysate at 40 μg
Primary: Anti-GALNT13 (TMAB-00737) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 64 kDa
Observed band size: 62 kDa
应用
WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Golgi apparatus membrane; Single pass type II membrane protein.
组织特异性Specifically expressed in neuronal cells. Expressed in fetal brain, whole adult brain, cerebral cortex and cerebellum. Not expressed in other tissues tested.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景The UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosamine) to serine and threonine residues onto various proteins, thereby initiating mucin-type O-linked glycosylation in the Golgi apparatus. GalNAc-T13 (Polypeptide N-acetylgalactosaminyltransferase 13), also known as UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13, is a 556 amino acid protein that displays much stronger enzymatic activity than GalNAc-1 towards GalNAc transfer to mucin peptides such as Muc5a and Muc7. The N-terminal domain is involved in substrate binding and manganese coordination, while the C-terminal domain is involved in UDP-Gal binding and catalytic reaction. With specific expression in the central nervous system, GalNAc-T13 may be responsible for the synthesis of Tn antigen in neuronal cells, which is a universal carcinoma marker on malignant cells.
抗原信息
免疫原
KLH conjugated synthetic peptide: human GALNT13/GalNAc-T13
抗原种属
Human
基因名称
GALNT13
基因ID
114805
蛋白名称
Polypeptide N-acetylgalactosaminyltransferase 13
Uniprot ID
Q8IUC8
功能
GALNT13 is a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAcT; EC 2.4.1.41) family, which initiate O-linked glycosylation of mucins by the initial transfer of N-acetylgalactosamine (GalNAc) with an alpha-linkage to a serine or threonine residue. It is specifically expressed in neuronal cells; expressed in fetal brain, whole adult brain, cerebral cortex and cerebellum; not expressed in other tissues tested. There are two named isoforms.
化学信息
分子量Theoretical: 64 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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