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Anti-Cadherin 8/CDH8 Antibody (2O370) 是一种 Rabbit 抗体,靶向 Cadherin 8/CDH8。Anti-Cadherin 8/CDH8 Antibody (2O370) 可用于 ELISA。
Anti-Cadherin 8/CDH8 Antibody (2O370) 是一种 Rabbit 抗体,靶向 Cadherin 8/CDH8。Anti-Cadherin 8/CDH8 Antibody (2O370) 可用于 ELISA。
产品描述 | Anti-Cadherin 8/CDH8 Antibody (2O370) is a Rabbit antibody targeting Cadherin 8/CDH8. Anti-Cadherin 8/CDH8 Antibody (2O370) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 2O370 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human Cadherin-8 / CDH8 (rh Cadherin-8 / CDH8; TMPY-01038; NP_001787.2; Met1-Met621). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Cadherins are integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Type I cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of five subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Cadherin 8, also known as CDH 8, is a type II classical cadherin belonging to the cadherin superfamily. As mainly expressed in brain, CDH8 is found in certain nerve cell lines, such as retinoblasts, glioma cells and neuroblasts, and is putatively involved in synaptic adhesion, axon outgrowth and guidance. Human Cadherin 8 is a 799 amino acid single-pass type Itransmembrane protein with a putative 29 aa signal sequence, and a 32 aa propeptide, a 56 aa mature extracellular domain, a 21 aa transmembrane domain and a 157 aa cytoplasmic domain. The human, mouse and rat proteins share approximately 98% homology. |
偶联 | Unconjugated |
免疫原 | Recombinant Human Cadherin-8 / CDH8 Protein (TMPY-01038) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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