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Anti-HGF Antibody (2L382)

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Anti-HGF Antibody (2L382)
产品编号 TMAY-03833
别名 肝细胞生长因子, scatter factor), hepatocyte growth factor (hepapoietin A

Anti-HGF Antibody (2L382) 是一种 Rabbit 抗体,靶向 HGF。Anti-HGF Antibody (2L382) 可用于 ELISA。

Anti-HGF Antibody (2L382)

Anti-HGF Antibody (2L382)

Rating icon 还可以
Anti-HGF Antibody (2L382)
产品编号 TMAY-03833 别名 肝细胞生长因子, scatter factor), hepatocyte growth factor (hepapoietin A

Anti-HGF Antibody (2L382) 是一种 Rabbit 抗体,靶向 HGF。Anti-HGF Antibody (2L382) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,294
5日内发货
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TargetMol 的所有产品仅用作科学研究或药证申报,不能被用于人体,我们不向个人提供产品和服务。请您遵守承诺用途,不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
化合物带有盐酸盐离子、硫酸盐离子等是否和其本身有什么区别?盐形式和游离态有什么区别?
盐和非盐形式化合物的活性分子是一样的,在生物实验中起到的效果也一致,活性和使用方法都是一样的。只是由于呈盐不同,物理性质比如溶解度会有差异。建议您根据溶解、实验需求进行选择。
如何选择某个靶点的特异性或总的抑制剂?特异性和非特异性的区别是什么?
抑制剂按照特异性分为广谱 pan 和特异性 selective 两种。Pan 为某个靶点总的抑制剂,对所有亚型或整个家族的成员都有抑制作用。Selective 抑制剂针对某个蛋白激酶的某个亚型或家族中某个成员抑制率特别高或有特异性抑制作用。 一般评价一个抑制剂的抑制效率主要看 IC50 值,IC50 值越低,说明抑制剂效率越高。建议您根据以上几个特征进行综合选择,也可联系技术帮您推荐相关抑制剂。
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产品介绍

生物活性
产品描述
Anti-HGF Antibody (2L382) is a Rabbit antibody targeting HGF. Anti-HGF Antibody (2L382) can be used in ELISA.
别名肝细胞生长因子, scatter factor), hepatocyte growth factor (hepapoietin A
Ig Type
Rabbit IgG
克隆号
2L382
交叉反应
Rat
应用
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Rat HGF/Hepatocyte Growth Factor (rR HGF/Hepatocyte Growth Factor; TMPY-03246; NP_058713.1; Met1-Leu728).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Hepatocyte growth factor, also known as HGF, contains 4 kringle domains, 1 PAN domain, and 1 peptidase S1 domain. It belongs to the peptidase S1 family, plasminogen subfamily. The hepatocyte growth factor is secreted by mesenchymal cells as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor, and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility and matrix invasion give it a central role in angiogenesis, tumorogenesis, and tissue regeneration. HGF is a potent mitogen for mature parenchymal hepatocyte cells, seems to be an hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. HGF has no detectable protease activity. Defects in hepatocyte growth factor are the cause of deafness autosomal recessive type 39. A form of profound prelingual sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Rat HGF/Hepatocyte Growth Factor Protein (TMPY-03246)
抗原种属
Rat
研究领域
Cancer Drug Targets
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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