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Anti-LAMP2 Antibody (3I840)

货号 TMAB-08212 一键复制产品信息
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Anti-LAMP2 Antibody (3I840) 是一种 Mouse 抗体,靶向 LAMP2。Anti-LAMP2 Antibody (3I840) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-LAMP2 Antibody (3I840)

一键复制产品信息
Rating icon 还可以
货号 TMAB-08212

Anti-LAMP2 Antibody (3I840) 是一种 Mouse 抗体,靶向 LAMP2。Anti-LAMP2 Antibody (3I840) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-LAMP2 Antibody (3I840)
规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
库存状态实时更新,以官网显示为准,现货产品可直接加购物车下单
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产品介绍


生物活性
产品描述
Anti-LAMP2 Antibody (3I840) is a Mouse antibody targeting LAMP2. Anti-LAMP2 Antibody (3I840) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG1, k
克隆号
3I840
反应种属
Human
验证活性
1. 25 μg total protein per lane of various lysates (see on figure) probed with LAMP2 monoclonal antibody, unconjugated (TMAB-08212) at 1:500 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
2. Paraformaldehyde-fixed, paraffin embedded Human Liver Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with LAMP2 Monoclonal Antibody, Unconjugated (TMAB-08212) at 1: 200 overnight at 4°C, followed by conjugation to the AffiniPure Goat Anti-Mouse IgG H&L-HRP and DAB staining.
3. Paraformaldehyde-fixed, paraffin embedded Human Thyroid Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with LAMP2 Monoclonal Antibody, Unconjugated (TMAB-08212) at 1: 200 overnight at 4°C, followed by conjugation to the AffiniPure Goat Anti-Mouse IgG H&L-HRP and DAB staining.
4. Paraformaldehyde-fixed, paraffin embedded Human Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with LAMP2 Monoclonal Antibody, Unconjugated (TMAB-08212) at 1: 200 overnight at 4°C, followed by conjugation to the AffiniPure Goat Anti-Mouse IgG H&L-HRP and DAB staining.
5. Paraformaldehyde-fixed, paraffin embedded Human Kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with LAMP2 Monoclonal Antibody, Unconjugated (TMAB-08212) at 1: 200 overnight at 4°C, followed by conjugation to the AffiniPure Goat Anti-Mouse IgG H&L-HRP and DAB staining.
6. Paraformaldehyde-fixed, paraffin embedded Human Placenta; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with LAMP2 Monoclonal Antibody, Unconjugated (TMAB-08212) at 1: 200 overnight at 4°C, followed by conjugation to the AffiniPure Goat Anti-Mouse IgG H&L-HRP and DAB staining.
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=This protein shuttles between lysosomes, endosomes, and the plasma membrane.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by the LAMP2 gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands and is thought to play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of the gene produces two known products, LAMP2a and LAMP2b. Isoform LAMP2a is highly expressed in placenta, lung and liver and has low expression in brain and skeletal muscle. The isoform detected by this antibody, LAMP2b, is highly expressed in skeletal muscle less so in brain, placental, lung, kidney and pancreas and has very low expression in liver.
抗原信息
免疫原
Recombinant Protein: human LAMP2
抗原种属
Human
基因名称
LAMP2
基因ID
蛋白名称
Lysosome-associated membrane glycoprotein 2
Uniprot ID
功能
Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter-and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens.
化学信息
分子量Theoretical: 45 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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