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Anti-CD31/PECAM-1 Antibody-FITC (2H633) 是一种 FITC-conjugated Mouse 抗体,靶向 CD31/PECAM-1。Anti-CD31/PECAM-1 Antibody-FITC (2H633) 可用于 FCM。
Anti-CD31/PECAM-1 Antibody-FITC (2H633) 是一种 FITC-conjugated Mouse 抗体,靶向 CD31/PECAM-1。Anti-CD31/PECAM-1 Antibody-FITC (2H633) 可用于 FCM。
产品描述 | Anti-CD31/PECAM-1 Antibody-FITC (2H633) is a FITC-conjugated Mouse antibody targeting CD31/PECAM-1. Anti-CD31/PECAM-1 Antibody-FITC (2H633) can be used in FCM. |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 2H633 |
交叉反应 | Human |
验证活性 | Profile of peripheral blood lymphocytes and blood monocytes analyzed by flow cytometry. |
应用 | FCM |
推荐剂量 | 10 μl/Test, 0.1 mg/ml |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD31 / PECAM1 (rhCD31; TMPY-00970; Met 1-Lys 601; EAW94208.1) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
研究背景 | The Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 130-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, monocytes, neutrophils, and certain T cell subsets. CD31 protein is also expressed in certain tumors, including epithelioid hemangioendothelioma, other vascular tumors, and histiocytic malignancies. CD31 plays a key role in removing aged neutrophils and tissue regeneration. CD31 protein mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin αvβ3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development. |
偶联 | FITC |
免疫原 | Recombinant Human CD31 protein (TMPY-00970) |
抗原种属 | Human |
研究领域 | Hemangioblast Markers, ITIM/ITAM Immunoreceptors and Related Molecules |
储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
运输方式 | Shipping with blue ice. |
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