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顶部产品介绍化学信息储存和溶解信息计算器技术支持

Hepcidin/HAMP Protein, Mouse, Recombinant (GST)

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货号 TMPK-01170

别名 PLTR, LEAP-1, LEAP1, HFE2B, Hepc1, Hepc, Hamp1

Hepcidin, the main regulator of iron metabolism, is synthesized and released by hepatocytes in response to increased body iron concentration and inflammation. Deregulation of hepcidin expression is a common feature of genetic and acquired iron disorders: in Hereditary Hemochromatosis (HH) and iron-loading anemias low hepcidin causes iron overload, while in Iron Refractory Iron Deficiency Anemia (IRIDA) and anemia of inflammation (AI), high hepcidin levels induce iron-restricted erythropoiesis.

Hepcidin/HAMP Protein, Mouse, Recombinant (GST)
其他形式的 “Hepcidin/HAMP Protein, Mouse, Recombinant (GST)”:
Hepcidin/HAMP Protein, Human, Recombinant (GST)
Miltefosine

Hepcidin/HAMP Protein, Mouse, Recombinant (GST)

一键复制产品信息
Rating icon 还可以
货号 TMPK-01170 别名 PLTR, LEAP-1, LEAP1, HFE2B, Hepc1, Hepc, Hamp1

Hepcidin, the main regulator of iron metabolism, is synthesized and released by hepatocytes in response to increased body iron concentration and inflammation. Deregulation of hepcidin expression is a common feature of genetic and acquired iron disorders: in Hereditary Hemochromatosis (HH) and iron-loading anemias low hepcidin causes iron overload, while in Iron Refractory Iron Deficiency Anemia (IRIDA) and anemia of inflammation (AI), high hepcidin levels induce iron-restricted erythropoiesis.

规格价格库存数量
5 μg
¥ 343
6-8日内发货
10 μg
¥ 549
6-8日内发货
20 μg
¥ 898
5日内发货
50 μg
¥ 1,760
5日内发货
100 μg
¥ 2,960
5日内发货
200 μg
¥ 5,350
5日内发货
500 μg
¥ 11,800
5日内发货
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产品介绍

生物活性
产品描述
Hepcidin, the main regulator of iron metabolism, is synthesized and released by hepatocytes in response to increased body iron concentration and inflammation. Deregulation of hepcidin expression is a common feature of genetic and acquired iron disorders: in Hereditary Hemochromatosis (HH) and iron-loading anemias low hepcidin causes iron overload, while in Iron Refractory Iron Deficiency Anemia (IRIDA) and anemia of inflammation (AI), high hepcidin levels induce iron-restricted erythropoiesis.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
Hepcidin, the main regulator of iron metabolism, is synthesized and released by hepatocytes in response to increased body iron concentration and inflammation. Deregulation of hepcidin expression is a common feature of genetic and acquired iron disorders: in Hereditary Hemochromatosis (HH) and iron-loading anemias low hepcidin causes iron overload, while in Iron Refractory Iron Deficiency Anemia (IRIDA) and anemia of inflammation (AI), high hepcidin levels induce iron-restricted erythropoiesis.
种属
Mouse
表达系统
E. coli
标签N-GST
蛋白编号Q9EQ21
蛋白构建Asp59-Thr83
蛋白纯度
> 95% as determined by Tris-Bis PAGE
蛋白性状Lyophilized powder
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM Tris-HCl, 150 mM NaCl, 2 mM DTT (pH 7.5). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名PLTR, LEAP-1, LEAP1, HFE2B, Hepc1, Hepc, Hamp1
内毒素< 1.0 EU/μg of the protein as determined by the LAL method.
化学信息
分子量29.05 kDa (predicted) same as Tris-Bis PAGE result.
储存&溶解度
运输方式In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
存储

计算器

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剂量转换

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.

关键词

LEAP 1
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