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Anti-Ku70 Antibody (6Y615) 是一种 Rabbit 抗体,靶向 Ku70。Anti-Ku70 Antibody (6Y615) 可用于 WB,IP,ICC/IF,IHC,FCM。
Anti-Ku70 Antibody (6Y615) 是一种 Rabbit 抗体,靶向 Ku70。Anti-Ku70 Antibody (6Y615) 可用于 WB,IP,ICC/IF,IHC,FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,495 | 5日内发货 | |
100 μL | ¥ 2,480 | 5日内发货 |
产品描述 | Anti-Ku70 Antibody (6Y615) is a Rabbit antibody targeting Ku70. Anti-Ku70 Antibody (6Y615) can be used in WB,IP,ICC/IF,IHC,FCM. |
别名 | XRCC6_HUMAN, Xrcc6, XRCC 6, X-ray repair cross-complementing protein 6, X-ray repair complementing defective repair in Chinese hamster cells 6, X ray repair complementing defective repair in Chinese hamster cells 6, TLAA, Thyroid-lupus autoantigen, Thyroid lupus autoantigen p70, Thyroid lupus autoantigen, Thyroid autoantigen 70kD (Ku antigen), Thyroid autoantigen, ML8, Lupus Ku autoantigen protein p70, Kup70, Ku70 DNA binding component of DNA-dependent proteinkinase complex (thyroid autoantigen 70 kDa, Ku p70, Ku autoantigen, 70kDa, Ku autoantigen p70 subunit, Ku 70, G22P1, DNA repair protein XRCC6, CTCBF, CTC75, CTC box-binding factor 75 kDa subunit, CTC box binding factor 75 kDa subunit, ATP-dependent DNA helicase II 70 kDa subunit, ATP-dependent DNA helicase 2 subunit 1, ATP dependent DNA helicase II 70 kDa subunit, ATP dependent DNA helicase 2 subunit 1, 70 kDa subunit of Ku antigen, 5''-dRP lyase Ku70, 5''-deoxyribose-5-phosphate lyase Ku70 |
Ig Type | IgG |
交叉反应 | Human |
应用 | |
推荐剂量 | WB: 1:500-2000; IHC: 1:50-200; ICC/IF: 1:50-200; IP: 1:10-50; FCM: 1:50-100 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | The Ku protein is localized in the nucleus and is composed of subunits referred to as Ku-70 (p70) and Ku-86 (p86) which is also known by the synonym Ku-80 or (p80). Ku was first described as an autoantigen to which antibodies were produced in a patient with scleroderma polymyositis overlap syndrome, and was later found in the sera of patients with other rheumatic diseases. Both subunits of the Ku protein have been cloned, and a number of functions have been proposed for Ku, including cell signaling, DNA replication and transcriptional activation. Ku is involved in Pol II-directed transcription by virtue of its DNA binding activity, serving as the regulatory component of the DNA-associated protein kinase that phosphorylates Pol II and transcription factor Sp. Ku proteins also activate transcription from the U1 small nuclear RNA and the human transferrin receptor gene promoters. A Ku-related protein designated the enhancer 1 binding factor (E1BF), composed of two subunits, has been identified as a positive regulator of RNA polymerase I transcription initiation. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 70 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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