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Anti-CST6 Antibody (1U151)
还可以产品编号 TMAY-00830
Anti-CST6 Antibody (1U151) 是一种 Mouse 抗体，靶向 CST6。Anti-CST6 Antibody (1U151) 可用于 IHC-P。
Anti-CST6 Antibody (1U151)
Anti-CST6 Antibody (1U151)
还可以产品编号 TMAY-00830
Anti-CST6 Antibody (1U151) 是一种 Mouse 抗体，靶向 CST6。Anti-CST6 Antibody (1U151) 可用于 IHC-P。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CST6 Antibody (1U151) is a Mouse antibody targeting CST6. Anti-CST6 Antibody (1U151) can be used in IHC-P. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 1U151 |
| 交叉反应 | Human |
| 验证活性 | Immunochemical staining of human CST6 in human skin with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:50-1:200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Cystatin E / CST6 (rh Cystatin E / CST6; TMPY-00768; NP_001314.1; Met1-Met149). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Cystatin E/M, also referred to as CST6, is a member of type 2 cysteine proteinase inhibitors of the cystatin superfamily, and inhibits papain and cathepsin B. Cystatin E is a low molecular mass secreted protein existing in both a glycosylated (17 kDa) and an unglycosylated (14 kDa) form, with two characteristic intrachain disulfide bridges. Expression of cystatin M/E is found to be restricted to the epidermis, more specifically in the stratum granulosum, sweat glands, sebaceous glands, and the hair follicles. In addition to its function as a cysteine protease inhibitor, cystatin M/E also serves as a target for cross-linking by transglutaminases. Accordingly, cystatin M/E was suggested to be involved in barrier formation and maintenance. Furthermore, studies have revealed that cystatin M/E is frequently epigenetically inactivated during breast carcinogenesis, and thus be regarded as a candidate of tumour suppressor gene. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human Cystatin E / CST6 protein (TMPY-00768) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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