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Anti-FOXA2 Antibody (8N555)
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产品编号 TMAC-01532
别名 Transcription factor 3B(TCF-3B), HNF-3-beta, HNF3B, TCF3B, HNF-3B, Hepatocyte nuclear factor 3-beta, FOXA 2, Forkhead box protein A2
Anti-FOXA2 Antibody (8N555) 是一种 Rabbit 抗体，靶向 FOXA2。Anti-FOXA2 Antibody (8N555) 可用于 WB,ICC/IF。
Anti-FOXA2 Antibody (8N555)
Anti-FOXA2 Antibody (8N555)
还可以产品编号 TMAC-01532 别名 Transcription factor 3B(TCF-3B), HNF-3-beta, HNF3B, TCF3B, HNF-3B, Hepatocyte nuclear factor 3-beta, FOXA 2, Forkhead box protein A2
Anti-FOXA2 Antibody (8N555) 是一种 Rabbit 抗体，靶向 FOXA2。Anti-FOXA2 Antibody (8N555) 可用于 WB,ICC/IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,485 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-FOXA2 Antibody (8N555) is a Rabbit antibody targeting FOXA2. Anti-FOXA2 Antibody (8N555) can be used in WB,ICC/IF. |
| 别名 | Transcription factor 3B(TCF-3B), HNF-3-beta, HNF3B, TCF3B, HNF-3B, Hepatocyte nuclear factor 3-beta, FOXA 2, Forkhead box protein A2 |
| Ig Type | IgG |
| 交叉反应 | Human |
| 验证活性 | 1. Western blot analysis of FOXA2 on HT-29 cells lysates using anti-FOXA2 antibody at 1/500 dilution. |
| 应用 | |
| 推荐剂量 | WB: 1:1000-5000; ICC/IF: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally discribed as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 52 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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