Anti-ATP5O Antibody (8V358) is a Mouse antibody targeting ATP5O. Anti-ATP5O Antibody (8V358) can be used in WB,ICC/IF.

IgG1, Kappa

8V358

Human

WB: 1:1000-5000; ICC/IF: 1:100-500

Monoclonal

ATP5PO

ATP synthase subunit O, mitochondrial

Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.